6-Iodopurine as a Versatile Building Block for RNA Purine Architecture Modifications.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.1c00595
Abstract: Natural modified bases in RNA were found to be indispensable for basic biological processes. In addition, artificial RNA modifications have been a versatile toolbox for the study of RNA interference, structure, and dynamics. Here, we… read more here.
Keywords: block rna; rna; versatile building; iodopurine versatile ... See more keywords
Dihydro-2H-thiopyran-3(4H)-one-1,1-dioxide – a versatile building block for the synthesis of new thiopyran-based heterocyclic systems
Sign Up to like & getrecommendations! Published in 2018 at "New Journal of Chemistry"
DOI: 10.1039/c7nj03846a
Abstract: Three series of new cyclic sulfones have been prepared by a one-pot multi-component reaction (MCR) starting from the readily available dihydro-2H-thiopyran-3(4H)-one-1,1-dioxide. The in silico screening of the synthesized compounds revealed their high anti-inflammatory, antiarthritic, antiasthmatic… read more here.
Keywords: thiopyran one; dihydro thiopyran; versatile building; dioxide versatile ... See more keywords
Azido-perylenediimide: a versatile building block for CuAAC reactions and an alternative precursor for N-annulation
Sign Up to like & getrecommendations! Published in 2021 at "New Journal of Chemistry"
DOI: 10.1039/d1nj02130c
Abstract: Azido-perylenediimide readily transforms into N-annulated derivatives when exposed to light, and can be clicked in the dark. read more here.
Keywords: building block; cuaac reactions; block cuaac; versatile building ... See more keywords
N-Propargylamines: versatile building blocks in the construction of thiazole cores
Sign Up to like & getrecommendations! Published in 2017 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.13.61
Abstract: Thiazoles and their hydrogenated analogues are not only key structural units in a wide variety of natural products but they also constitute important building blocks in medicinal chemistry. Therefore, the synthesis of these compounds using… read more here.
Keywords: propargylamines versatile; building blocks; chemistry; blocks construction ... See more keywords