Rhodium-Catalyzed C-H Alkenylation/Electrocyclization Cascade Provides Dihydropyridines That Serve as Versatile Intermediates to Diverse Nitrogen Heterocycles.
Sign Up to like & getrecommendations! Published in 2021 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.1c00027
Abstract: ConspectusNitrogen heterocycles are present in approximately 60% of drugs, with nonplanar heterocycles incorporating stereogenic centers being of considerable interest to the fields of medicinal chemistry, chemical biology, and synthetic methods development. Over the past several… read more here.
Keywords: alkenylation electrocyclization; nitrogen heterocycles; electrocyclization cascade; versatile intermediates ... See more keywords
Unsubstituted Bambusurils: Post-Macrocyclization Modification of Versatile Intermediates
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DOI: 10.1021/acsomega.8b00497
Abstract: A new bambusuril derivative, (H)BU[6], lacking substituents on the ureidic nitrogen atoms, has been isolated and characterized. This macrocycle was prepared by the deprotection of bambusuril (PMB)BU[6]. (H)BU[6] is attractive for use as a starting… read more here.
Keywords: post macrocyclization; bambusurils post; macrocyclization modification; unsubstituted bambusurils ... See more keywords