Acetylcholinesterase: A Versatile Template to Coin Potent Modulators of Multiple Therapeutic Targets
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DOI: 10.1021/acs.accounts.3c00617
Abstract: Conspectus The enzyme acetylcholinesterase (AChE) hydrolyzes the neurotransmitter acetylcholine (ACh) at cholinergic synapses of the peripheral and central nervous system. Thus, it is a prime therapeutic target for diseases that occur with a cholinergic deficit,… read more here.
Keywords: acetylcholinesterase versatile; molecular hybridization; versatile template; gorge ... See more keywords