Molecular Simulation Studies on the Binding Selectivity of Type-I Inhibitors in the Complexes with ROS1 versus ALK
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DOI: 10.1021/acs.jcim.7b00019
Abstract: ROS1 and ALK are promising targets of anticancer drugs for non-small-cell lung cancer. Since they have 49% amide acid sequence homology in the kinases domain and 77% identity at the ATP binding area, some ALK… read more here.
Keywords: versus alk; inhibitor; alk; ros1 ... See more keywords