Kinetic Control of Parallel versus Antiparallel Amyloid Aggregation via Shape of the Growing Aggregate
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DOI: 10.1038/s41598-019-52238-x
Abstract: By combining atomistic and higher-level modelling with solution X-ray diffraction we analyse self-assembly pathways for the IFQINS hexapeptide, a bio-relevant amyloid former derived from human lysozyme. We verify that (at least) two metastable polymorphic structures… read more here.
Keywords: control parallel; shape; versus antiparallel; kinetic control ... See more keywords