Patient‐reported symptom burden and impact on daily activities in chronic graft‐versus‐host disease
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DOI: 10.1002/cam4.5209
Abstract: Chronic graft‐versus‐host disease (GVHD) is a potentially life‐threatening complication of allogeneic hematopoietic stem cell transplantation (HSCT) treatment for hematologic malignancies. There are limited patient‐reported data concerning symptom burden and effects on activities of daily living… read more here.
Keywords: symptom burden; chronic graft; patient reported; host disease ... See more keywords
Noncoding RNAs in diagnosis and prognosis of graft‐versus‐host disease (GVHD)
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DOI: 10.1002/jcp.30830
Abstract: Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is a functional therapy for a plethora of hematologic malignancies and immune disorders. Graft‐versus‐host disease (GVHD), on the other hand, is one of the major complications ahead of a… read more here.
Keywords: host disease; versus host; noncoding rnas; graft versus ... See more keywords
Microbiome: an emerging new frontier in graft‑versus‑host disease
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DOI: 10.1007/s00011-020-01419-w
Abstract: The field around the microbiome and graft-versus-host disease (GVHD) is rapidly evolving and so is its literature. Therefore, we consider it important to provide an update on our recent review “Microbiome: An Emerging New Frontier… read more here.
Keywords: versus host; graft versus; host; host disease ... See more keywords
Compound heterozygous DCLRE1C mutations lead to clinically typical Severe Combined Immunodeficiency presenting with Graft Versus Host Disease.
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DOI: 10.1007/s00251-021-01219-4
Abstract: Artemis (DCLRE1C) is involved in opening recombination-activating gene (RAG1/RAG2)-generated hairpins during V(D)J recombination, an essential process for the differentiation and maturation of T and B cells. Here, we reported a case of 5-month-old boy with… read more here.
Keywords: versus host; combined immunodeficiency; host disease; compound heterozygous ... See more keywords
High lymphocyte counts before antithymocyte globulin administration predict acute graft-versus-host disease
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DOI: 10.1007/s00277-020-04347-1
Abstract: Antithymocyte globulin (ATG) reduces severe acute and chronic graft-versus-host disease (GVHD) in allogeneic peripheral blood stem cell transplantation (PBSCT). However, risk factors for severe acute GVHD in PBSCT using ATG remain to be determined. We… read more here.
Keywords: lymphocyte counts; alc atg; versus host; host disease ... See more keywords
Resolution of acute intestinal graft-versus-host disease
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DOI: 10.1007/s00281-019-00769-w
Abstract: Allogeneic transplantation of hematopoietic stem cells (allo-HCT) represents an increasingly employed therapeutic approach to potentially cure patients suffering from life-threatening malignant and autoimmune disorders. Despite its lifesaving potential, immune-mediated allo-reactivity inherent to the allogeneic transplantation… read more here.
Keywords: resolution; versus host; disease; host disease ... See more keywords
Detection of systemic immunosuppressants in autologous serum eye drops (ASED) in patients with severe chronic ocular graft versus host disease
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DOI: 10.1007/s00417-020-04865-8
Abstract: Purpose Chronic graft versus host disease is a major consequence after allogeneic stem cell transplantation (allo-SCT) and has great impact on patients’ morbidity and mortality. Besides the skin, liver, and intestines, the eyes are most… read more here.
Keywords: systemic immunosuppressants; ased patients; versus host; disease ... See more keywords
Prophylaxis and treatment with mycophenolate mofetil in children with graft-versus-host disease undergoing allogeneic hematopoietic stem cell transplantation: a nationwide survey in Japan
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DOI: 10.1007/s12185-019-02601-5
Abstract: We investigated the safety and efficacy of mycophenolate mofetil (MMF) in the prevention and treatment of graft-versus-host disease (GVHD) using a nationwide retrospective survey in Japanese children undergoing hematopoietic stem cell transplantation (HSCT). Overall, 141… read more here.
Keywords: treatment; versus host; prophylaxis; gvhd ... See more keywords
Impact of graft-versus-host disease on the clinical outcome of allogeneic hematopoietic stem cell transplantation for non-malignant diseases
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DOI: 10.1007/s12185-020-02839-4
Abstract: The impact of acute and chronic graft-versus-host disease (GVHD) on clinical outcomes was retrospectively analyzed in 960 patients with non-malignant diseases (NMD) who underwent a first allogeneic hematopoietic stem cell transplantation (HSCT). Grade III–IV acute GVHD (but not… read more here.
Keywords: associated lower; significantly associated; versus host; gvhd ... See more keywords
Oral chronic graft-versus-host disease: What the general dental practitioner needs to know.
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DOI: 10.1016/j.adaj.2020.08.001
Abstract: BACKGROUND Long-term survivors of allogeneic hematopoietic cell transplantation will increasingly seek care from dental providers. METHODS The authors highlight the importance of minimizing oral symptoms and complications associated with oral chronic graft-versus-host-disease (cGVHD). RESULTS Chronic… read more here.
Keywords: cgvhd; versus host; oral chronic; host disease ... See more keywords
Prevalence of PersistentCorneal Epithelial Defects in Chronic Ocular Graft- Versus-Host Disease.
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DOI: 10.1016/j.ajo.2020.05.035
Abstract: PURPOSE To establish the prevalence, clinical characteristics, and risk factors for persistent corneal epithelial defects (PED) in patients with chronic ocular graft-versus-host disease (oGVHD) and to determine visual outcomes after healing. DESIGN Retrospective cohort study… read more here.
Keywords: versus host; prevalence; epithelial defects; ocular graft ... See more keywords