Pre-Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft-Versus-Host Disease in Systemic Organs.
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DOI: 10.1002/advs.202415982
Abstract: Acute graft-versus-host disease (aGvHD) remains a significant clinical challenge, with no optimal treatment despite advancements in medical science. This life-threatening condition, characterized by multi-organ involvement and high mortality, is increasingly linked to the gut microbiota.… read more here.
Keywords: disease; host disease; administration; versus host ... See more keywords
Toward Improving Initial Therapy of Acute Graft Versus Host Disease
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DOI: 10.1002/ajh.27593
Abstract: Acute graft versus host disease (aGVHD) is a major complication of hematopoietic stem cell transplantation; it results from donor‐derived immune response against host tissues and typically involves the liver, skin and the GI tract. The… read more here.
Keywords: host; host disease; versus host; graft versus ... See more keywords
Patient‐reported symptom burden and impact on daily activities in chronic graft‐versus‐host disease
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DOI: 10.1002/cam4.5209
Abstract: Chronic graft‐versus‐host disease (GVHD) is a potentially life‐threatening complication of allogeneic hematopoietic stem cell transplantation (HSCT) treatment for hematologic malignancies. There are limited patient‐reported data concerning symptom burden and effects on activities of daily living… read more here.
Keywords: symptom burden; chronic graft; patient reported; host disease ... See more keywords
Monitoring plasma regenerating islet-derived 3α and citrulline levels during pediatric allogeneic hematopoietic stem cell transplantation to predict acute gastrointestinal graft-versus-host disease.
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DOI: 10.1002/ijc.70205
Abstract: Acute graft‐versus‐host disease (aGvHD) with gastrointestinal (GI) involvement is a significant cause of transplant‐related morbidity and mortality following allogeneic hematopoietic stem cell transplantation (HSCT). Although elevated plasma Regenerating islet‐derived 3α (REG3α) and reduced citrulline levels… read more here.
Keywords: citrulline; host disease; citrulline levels; versus host ... See more keywords
Noncoding RNAs in diagnosis and prognosis of graft‐versus‐host disease (GVHD)
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DOI: 10.1002/jcp.30830
Abstract: Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is a functional therapy for a plethora of hematologic malignancies and immune disorders. Graft‐versus‐host disease (GVHD), on the other hand, is one of the major complications ahead of a… read more here.
Keywords: host disease; versus host; noncoding rnas; graft versus ... See more keywords
Microbiome: an emerging new frontier in graft‑versus‑host disease
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DOI: 10.1007/s00011-020-01419-w
Abstract: The field around the microbiome and graft-versus-host disease (GVHD) is rapidly evolving and so is its literature. Therefore, we consider it important to provide an update on our recent review “Microbiome: An Emerging New Frontier… read more here.
Keywords: versus host; graft versus; host; host disease ... See more keywords
Compound heterozygous DCLRE1C mutations lead to clinically typical Severe Combined Immunodeficiency presenting with Graft Versus Host Disease.
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DOI: 10.1007/s00251-021-01219-4
Abstract: Artemis (DCLRE1C) is involved in opening recombination-activating gene (RAG1/RAG2)-generated hairpins during V(D)J recombination, an essential process for the differentiation and maturation of T and B cells. Here, we reported a case of 5-month-old boy with… read more here.
Keywords: versus host; combined immunodeficiency; host disease; compound heterozygous ... See more keywords
High lymphocyte counts before antithymocyte globulin administration predict acute graft-versus-host disease
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DOI: 10.1007/s00277-020-04347-1
Abstract: Antithymocyte globulin (ATG) reduces severe acute and chronic graft-versus-host disease (GVHD) in allogeneic peripheral blood stem cell transplantation (PBSCT). However, risk factors for severe acute GVHD in PBSCT using ATG remain to be determined. We… read more here.
Keywords: lymphocyte counts; alc atg; versus host; host disease ... See more keywords
Recent advances in acute gastrointestinal graft versus host disease (aGvHD): aspects of steroid-resistant disease
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DOI: 10.1007/s00277-024-05952-0
Abstract: Acute Graft versus Host Disease (aGvHD) is a common immunological complication occurring in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Moreover, aGvHD is associated with a higher risk of infections and metabolic complications, affecting… read more here.
Keywords: disease; host disease; versus host; graft versus ... See more keywords
Resolution of acute intestinal graft-versus-host disease
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DOI: 10.1007/s00281-019-00769-w
Abstract: Allogeneic transplantation of hematopoietic stem cells (allo-HCT) represents an increasingly employed therapeutic approach to potentially cure patients suffering from life-threatening malignant and autoimmune disorders. Despite its lifesaving potential, immune-mediated allo-reactivity inherent to the allogeneic transplantation… read more here.
Keywords: resolution; versus host; disease; host disease ... See more keywords
Detection of systemic immunosuppressants in autologous serum eye drops (ASED) in patients with severe chronic ocular graft versus host disease
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DOI: 10.1007/s00417-020-04865-8
Abstract: Purpose Chronic graft versus host disease is a major consequence after allogeneic stem cell transplantation (allo-SCT) and has great impact on patients’ morbidity and mortality. Besides the skin, liver, and intestines, the eyes are most… read more here.
Keywords: systemic immunosuppressants; ased patients; versus host; disease ... See more keywords