Post‐transplant strategies to improve relapse‐free survival in childhood leukemia: Whole blood donor lymphocyte infusions and lenalidomide for inducing graft‐versus‐leukemia effect
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Transplantation"
DOI: 10.1111/petr.14293
Abstract: Post‐transplant graft‐versus‐leukemia (GVL) effect has been shown to be an important determinant of a successful outcome following hematopoietic stem cell transplantation (HSCT) in children with acute leukemia. read more here.
Keywords: post transplant; graft versus; leukemia; versus leukemia ... See more keywords
Innovations in conditioning and post-transplant maintenance in AML: genomically informed revelations on the graft-versus-leukemia effect
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1359113
Abstract: Acute Myeloid Leukemia (AML) is the prototype of cancer genomics as it was the first published cancer genome. Large-scale next generation/massively parallel sequencing efforts have identified recurrent alterations that inform prognosis and have guided the… read more here.
Keywords: gvl effect; effect; genomically informed; versus leukemia ... See more keywords
Targeting Histone Deacetylases to Modulate Graft-Versus-Host Disease and Graft-Versus-Leukemia
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21124281
Abstract: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the main therapeutic strategy for patients with both malignant and nonmalignant disorders. The therapeutic benefits of allo-HSCT in malignant disorders are primarily derived from the graft-versus-leukemia (GvL) effect,… read more here.
Keywords: versus leukemia; graft; versus host; graft versus ... See more keywords