Influence of Metastatic Bone Lesion Type and Tumor Origin on Human Vertebral Bone Architecture, Matrix Quality, and Mechanical Properties
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DOI: 10.1002/jbmr.4539
Abstract: Metastatic spine disease is incurable, causing increased vertebral fracture risk and severe patient morbidity. Here, we demonstrate that osteolytic, osteosclerotic, and mixed bone metastasis uniquely modify human vertebral bone architecture and quality, affecting vertebral strength… read more here.
Keywords: bone architecture; vertebral strength; bone; human vertebral ... See more keywords
Prediction of incident vertebral fracture using CT-based finite element analysis
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DOI: 10.1007/s00198-018-4716-1
Abstract: SummaryPrior studies show vertebral strength from computed tomography-based finite element analysis may be associated with vertebral fracture risk. We found vertebral strength had a strong association with new vertebral fractures, suggesting that vertebral strength measures… read more here.
Keywords: strength; based finite; incident vertebral; vertebral strength ... See more keywords
Stiffness and Strain Properties Derived From Digital Tomosynthesis-based Digital Volume Correlation Predict Vertebral Strength Independently From Bone Mineral Density.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4056196
Abstract: Vertebral fractures are the most common osteoporotic fractures, but their prediction using standard bone mineral density (BMD) measurements from dual energy x-ray absorptiometry (DXA) is limited in accuracy. Stiffness, displacement and strain distribution properties derived… read more here.
Keywords: strength; mineral density; dts dvc; vertebral strength ... See more keywords