Chimeric Zika viruses containing structural protein genes of insect-specific flaviviruses cannot replicate in vertebrate cells due to entry and post-translational restrictions.
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DOI: 10.1016/j.virol.2021.03.014
Abstract: Long Pine Key virus (LPKV) and Lammi virus are insect-specific flaviviruses that phylogenetically affiliate with dual-host flaviviruses. The goal of this study was to provide insight into the genetic determinants that condition this host range… read more here.
Keywords: vertebrate cells; insect specific; specific flaviviruses; entry ... See more keywords