linc-mipep and linc-wrb encode micropeptides that regulate chromatin accessibility in vertebrate-specific neural cells
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.07.21.501032
Abstract: Thousands of long intergenic non-coding RNAs (lincRNAs) are transcribed throughout the vertebrate genome. A subset of lincRNAs enriched in developing brains has recently been found to contain cryptic open reading frames and are speculated to… read more here.
Keywords: linc mipep; vertebrate specific; vertebrate; encode micropeptides ... See more keywords
Genetic evidence for splicing-dependent structural and functional plasticity in CASK protein
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Genetics"
DOI: 10.1136/jmg-2023-109747
Abstract: Background Pontocerebellar hypoplasia (PCH) may present with supratentorial phenotypes and is often accompanied by microcephaly. Damaging mutations in the X-linked gene CASK produce self-limiting microcephaly with PCH in females but are often lethal in males.… read more here.
Keywords: genetic evidence; cask protein; function; vertebrate specific ... See more keywords