Remission and Relapse of Dyslipidemia After Vertical Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass in a Racially and Ethnically Diverse Population
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.33843
Abstract: Key Points Question Do dyslipidemia outcomes up to 4 years after surgery differ between patients undergoing vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB)? Findings This comparative effectiveness study included 8265 racially and ethnically… read more here.
Keywords: roux gastric; racially ethnically; gastric bypass; sleeve gastrectomy ... See more keywords
β Cell GLP-1R Signaling Alters α Cell Proglucagon Processing after Vertical Sleeve Gastrectomy in Mice
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.03.120
Abstract: SUMMARY Bariatric surgery, such as vertical sleeve gastrectomy (VSG), causes high rates of type 2 diabetes remission and remarkable increases in postprandial glucagon-like peptide-1 (GLP-1) secretion. GLP-1 plays a critical role in islet function by… read more here.
Keywords: vertical sleeve; glp; glp signaling; sleeve gastrectomy ... See more keywords
A nonhuman primate model of vertical sleeve gastrectomy facilitates mechanistic and translational research in human obesity
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.103421
Abstract: Summary The obesity epidemic significantly contributes to overall morbidity and mortality. Bariatric surgery is the gold standard treatment for obesity and metabolic dysfunction, yet the mechanisms by which it exerts metabolic benefit remain unclear. Here,… read more here.
Keywords: model vertical; obesity; vertical sleeve; model ... See more keywords
Robotic-assisted vertical sleeve gastrectomy in adolescents: Do BMI limits apply?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2022.01.033
Abstract: BACKGROUND Robotic-assisted vertical sleeve gastrectomy (VSG) in adolescent patients has been shown to have comparable outcomes to laparoscopic VSG. Recent data suggests that metabolic and bariatric surgery (performed using robotic and laparoscopic techniques) in patients… read more here.
Keywords: group; adolescents bmi; assisted vertical; robotic assisted ... See more keywords
Liver-Expressed Antimicrobial Peptide 2 is a Hepatokine that Predicts Weight Loss and Complete Remission of Type 2 Diabetes Mellitus After Vertical Sleeve Gastrectomy in Japanese Individuals.
Sign Up to like & getrecommendations! Published in 2023 at "Obesity facts"
DOI: 10.1159/000530733
Abstract: INTRODUCTION Vertical sleeve gastrectomy (VSG) is considered one of the most effective treatments for sustained weight loss and complete remission of type 2 diabetes mellitus (CR-T2DM). Liver-expressed antimicrobial peptide 2 (LEAP2), a ghrelin receptor antagonist… read more here.
Keywords: vertical sleeve; weight loss; loss; serum leap2 ... See more keywords
Vertical sleeve gastrectomy improves ventilatory drive through a leptin-dependent mechanism.
Sign Up to like & getrecommendations! Published in 2019 at "JCI insight"
DOI: 10.1172/jci.insight.124469
Abstract: Obesity hypoventilation syndrome (OHS) is a serious disorder characterized by daytime hypercapnia, disordered breathing, and a reduction in chemosensitivity. Vertical sleeve gastrectomy (VSG), a bariatric surgical procedure resulting in weight loss and weight-independent improvements in… read more here.
Keywords: vertical sleeve; leptin dependent; leptin; dependent mechanism ... See more keywords
Anorexia and fat aversion induced by vertical sleeve gastrectomy is attenuated in neurotensin receptor 1 deficient mice.
Sign Up to like & getrecommendations! Published in 2021 at "Endocrinology"
DOI: 10.1210/endocr/bqab130
Abstract: Neurotensin (NT) is an anorexic gut hormone and neuropeptide that increases in circulation following bariatric surgery in humans and rodents. We sought to determine the contribution of NT to the metabolic efficacy of vertical sleeve… read more here.
Keywords: vertical sleeve; neurotensin receptor; vsg; sleeve gastrectomy ... See more keywords
Vertical Sleeve Gastrectomy Lowers SGLT2/Slc5a2 Expression in the Mouse Kidney.
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes"
DOI: 10.2337/db21-0768
Abstract: Bariatric surgery improves glucose homeostasis but the underlying mechanisms are not fully elucidated. Here, we show that the expression of sodium glucose cotransporter-2 (SGLT2/Slc5a2) is reduced in the kidney of lean and obese mice following… read more here.
Keywords: sglt2 slc5a2; surgery; expression; sleeve gastrectomy ... See more keywords
Vertical sleeve gastrectomy normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.1020576
Abstract: Objectives Glucocorticoids produced by the adrenal cortex are essential for the maintenance of metabolic homeostasis. Glucocorticoid activation is catalysed by 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1). Excess glucocorticoids are associated with insulin resistance and hyperglycaemia. A small… read more here.
Keywords: surgery; glucocorticoid action; sleeve gastrectomy; mice ... See more keywords
Vertical sleeve gastrectomy associates with airway hyperresponsiveness in a murine model of allergic airway disease and obesity
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1092277
Abstract: Introduction Asthma is a chronic airway inflammatory disease marked by airway inflammation, remodeling and hyperresponsiveness to allergens. Allergic asthma is normally well controlled through the use of beta-2-adrenergic agonists and inhaled corticosteroids; however, a subset… read more here.
Keywords: airway hyperresponsiveness; saline; surgery; mice ... See more keywords