Articles with "vesicant model" as a keyword



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Ebselen oxide attenuates mechlorethamine dermatotoxicity in the mouse ear vesicant model

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Published in 2018 at "Drug and Chemical Toxicology"

DOI: 10.1080/01480545.2018.1488858

Abstract: Abstract Mechlorethamine (HN2) is an alkylating agent and sulfur mustard mimetic. Topical exposure to HN2 is associated with tissue blistering. Previous work in our laboratory has shown that ebselen (EB-1) possesses anti-vesicant, anti-inflammatory, anti-bacterial, anti-fungal,… read more here.

Keywords: vesicant model; hn2; ebselen oxide; ear vesicant ... See more keywords