Quantitative and Multiplex Detection of Extracellular Vesicle‐Derived MicroRNA via Rolling Circle Amplification within Encoded Hydrogel Microparticles
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102332
Abstract: Extracellular vesicle‐derived microRNA (EV‐miRNA) represent a promising cancer biomarker for disease diagnosis and monitoring. However, existing techniques to detect EV‐miRNA rely on complex, bias‐prone strategies, and preprocessing steps, making absolute quantification highly challenging. This work… read more here.
Keywords: extracellular vesicle; derived microrna; detection; vesicle derived ... See more keywords
Emergent Motility of Self-Organized Particle-Giant Unilamellar Vesicle Assembly.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced materials"
DOI: 10.1002/adma.202512036
Abstract: Giant unilamellar vesicles (GUVs), soft cell-sized compartments formed through the self-assembly of lipid molecules, have long been utilized as model systems and passive carriers in membrane biophysics and biomedical applications. However, their potential as dynamically… read more here.
Keywords: motility; giant unilamellar; cell; self assembly ... See more keywords
Simulations of Myosin-Dependent Vesicle Clustering and Actin-Based Propulsion in Plant Cells.
Sign Up to like & getrecommendations! Published in 2025 at "Cytoskeleton"
DOI: 10.1002/cm.70058
Abstract: Vesicle trafficking is essential for plant cell growth, especially in tip-growing cells, where vesicles are directed to the expanding end of the cell through actin-myosin interactions. This study employs computer simulations to investigate vesicle dynamics… read more here.
Keywords: myosin; transport; vesicle clustering; plant ... See more keywords
Impact on NK cell functions of acute versus chronic exposure to extracellular vesicle‐associated MICA: Dual role in cancer immunosurveillance
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12176
Abstract: Abstract Natural killer (NK) cells are innate cytotoxic lymphocytes that play a key role in cancer immunosurveillance thanks to their ability to recognize and kill cancer cells. NKG2D is an activating receptor that binds to… read more here.
Keywords: cell; cancer immunosurveillance; vesicle; role cancer ... See more keywords
Analysis of extracellular vesicle DNA at the single‐vesicle level by nano‐flow cytometry
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12206
Abstract: Abstract It has been demonstrated recently that extracellular vesicles (EVs) carry DNA; however, many fundamental features of DNA in EVs (EV‐DNA) remain elusive. In this study, a laboratory‐built nano‐flow cytometer (nFCM) that can detect single… read more here.
Keywords: dna evs; dna; dna single; vesicle ... See more keywords
The development of extracellular vesicle markers for the fungal phytopathogen Colletotrichum higginsianum
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12216
Abstract: Abstract Fungal phytopathogens secrete extracellular vesicles (EVs) associated with enzymes and phytotoxic metabolites. While these vesicles are thought to promote infection, defining the true contents and functions of fungal EVs, as well as suitable protein… read more here.
Keywords: vesicle; colletotrichum higginsianum; phytopathogen colletotrichum;
Quantitative imaging of vesicle–protein interactions reveals close cooperation among proteins
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12322
Abstract: Abstract Membrane‐bound vesicles such as extracellular vesicles (EVs) can function as biochemical effectors on target cells. Docking of the vesicles onto recipient plasma membranes depends on their interaction with cell‐surface proteins, but a generalizable technique… read more here.
Keywords: quantitative imaging; surface; vesicle protein; protein interactions ... See more keywords
Glutamatergic Regulation of miRNA‐Containing Intraluminal Vesicle Trafficking and Extracellular Vesicle Secretion From Cortical Neurons
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.70100
Abstract: ABSTRACT Neuronal extracellular vesicles (microvesicles and exosomes) are emerging secreted vesicular signals that play important roles in the CNS. Currently, little is known about how glutamatergic signalling affects the subcellular localisation of exosome precursor intraluminal… read more here.
Keywords: hcd63 gfp; cortical neurons; secretion; hcd63 ... See more keywords
TurboID‐Mediated Profiling of Glioblastoma‐Derived Extracellular Vesicle Cargo Proteins
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.70158
Abstract: ABSTRACT Glioblastoma (GBM), the most aggressive primary brain tumour in adults, presents significant challenges due to its universal recurrence and limited survival rates. A key driver of GBM progression is the subpopulation of brain tumour‐initiating… read more here.
Keywords: cargo; turboid mediated; profiling glioblastoma; glioblastoma ... See more keywords
Visual Detection of pH and Biomolecular Interactions at Micromolar Concentrations Aided by a Trivalent Diacetylene-Based Vesicle
Sign Up to like & getrecommendations! Published in 2017 at "Macromolecular Chemistry and Physics"
DOI: 10.1002/macp.201700039
Abstract: A trivalent tris-(alkylenediynoic acid) is developed as a new monomer to prepare a poly(tris-(diacetylene)). Alkylenediynoic moieties, covalently linked to the gallic acid, lead to a high propensity for polymerization, resulting in blue poly(tris-(diacetylene)), within less… read more here.
Keywords: poly tris; tris diacetylene; vesicle; chromism ... See more keywords
Proteomic identification of intracellular vesicle trafficking and protein glycosylation requirements for lumen inflation in Ciona notochord
Sign Up to like & getrecommendations! Published in 2023 at "PROTEOMICS"
DOI: 10.1002/pmic.202200460
Abstract: Lumen formation and inflation are crucial steps for tubular organ morphogenesis, yet the underling mechanism remains largely unrevealed. Here, we applied 4D proteomics to screen the lumenogenesis‐related proteins and revealed the biological pathways potentially that… read more here.
Keywords: lumen inflation; glycosylation; vesicle trafficking; lumen formation ... See more keywords