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   Articles with "vesicle associated" as a keyword



DNA Nanowire Guided-Catalyzed Hairpin Assembly Nanoprobe for In Situ Profiling of Circulating Extracellular Vesicle-Associated MicroRNAs.

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recommendations! Published in 2022 at "ACS sensors"

DOI: 10.1021/acssensors.1c02717

Abstract: Extracellular vesicle-associated miRNAs (EV-miRNAs) are emerging as a new type of noninvasive biomarker for disease diagnosis. Their relatively low abundance, however, makes accurate detection challenging. Here, we designed a DNA nanowire guided-catalyzed hairpin assembly (NgCHA)… read more here.

Keywords: extracellular vesicle; hairpin assembly; vesicle associated; hairpin ... See more keywords

A signal-amplifiable biochip quantifies extracellular vesicle-associated RNAs for early cancer detection

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recommendations! Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-01942-1

Abstract: Detection of extracellular vesicle (EV)-associated RNAs with low expression levels in early-stage cancer remains a challenge and is highly valuable. Here, we report a nanoparticle-based biochip that could capture circulating EVs without isolation, brighten encapsulated… read more here.

Keywords: rnas early; extracellular vesicle; early cancer; vesicle associated ... See more keywords

The Ribosome Assembly Factor LSG1 Interacts with Vesicle-Associated Membrane Protein-Associated Proteins (VAPs)

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recommendations! Published in 2024 at "Molecular and Cellular Biology"

DOI: 10.1080/10985549.2024.2384600

Abstract: Abstract LSG1 is a conserved GTPase involved in ribosome assembly. It is required for the eviction of the nuclear export adapter NMD3 from the pre-60S subunit in the cytoplasm. In human cells, LSG1 has also… read more here.

Keywords: associated membrane; ribosome assembly; vesicle associated; protein associated ... See more keywords

Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence

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recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.955175

Abstract: Chronic inflammation is widely observed in aging, but it is unclear whether extracellular vesicles (EVs) play a role in chronic disease-associated senescence. In our study, LC/MS profiling revealed that senescent cell derived EVs (SEN EVs)… read more here.

Keywords: sen cells; extracellular vesicle; associated microrna; senescence ... See more keywords

Environmental Enrichment Upregulates Striatal Synaptic Vesicle-Associated Proteins and Improves Motor Function

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recommendations! Published in 2018 at "Frontiers in Neurology"

DOI: 10.3389/fneur.2018.00465

Abstract: Environmental enrichment (EE) is a therapeutic paradigm that consists of complex combinations of physical, cognitive, and social stimuli. The mechanisms underlying EE-mediated synaptic plasticity have yet to be fully elucidated. In this study, we investigated… read more here.

Keywords: motor function; vesicle; associated proteins; vesicle associated ... See more keywords