Extracellular Vesicle‐Based Antitumor Nanomedicines
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202403903
Abstract: Extracellular vesicles (EVs) have emerged as promising bioactive carriers for delivering therapeutic agents, including nucleic acids, proteins, and small‐molecule drugs, owing to their excellent physicochemical stability and biocompatibility. However, comprehensive reviews on the various types… read more here.
Keywords: antitumor nanomedicines; vesicle based; antitumor; extracellular vesicle ... See more keywords
Label-free characterization of an extracellular vesicle-based therapeutic.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of extracellular vesicles"
DOI: 10.1002/jev2.12156
Abstract: Interest in mesenchymal stem cell derived extracellular vesicles (MSC-EVs) as therapeutic agents has dramatically increased over the last decade. Current approaches to the characterization and quality control of EV-based therapeutics include particle tracking techniques, Western… read more here.
Keywords: extracellular vesicle; vesicle based; free characterization; characterization extracellular ... See more keywords
Nanoparticles binding to lipid membranes: from vesicle-based gels to vesicle tubulation and destruction.
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale"
DOI: 10.1039/c9nr06570a
Abstract: While cells offer numerous inspiring examples in which membrane morphology and function are controlled by interactions with viruses or proteins, we still lack design principles for controlling membrane morphology in synthetic systems. With experiments and… read more here.
Keywords: binding lipid; vesicle based; vesicle; energy ... See more keywords
Development of a novel human stratum corneum mimetic phospholipid vesicle-based permeation assay models for in vitro permeation studies
Sign Up to like & getrecommendations! Published in 2024 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2024.2331242
Abstract: Abstract Objectives To develop and evaluate a novel human stratum corneum (SC) mimetic phospholipid vesicle-based permeation assay (PVPASC) model for in vitro permeation studies. Significance Due to the increasing restrictions on the use of human… read more here.
Keywords: pvpasc model; permeation; vesicle based; permeation studies ... See more keywords
Vesicle-based formulations for pain treatment: a narrative review
Sign Up to like & getrecommendations! Published in 2024 at "Pain Reports"
DOI: 10.1097/pr9.0000000000001196
Abstract: Vesicle-based drug delivery offers promising solutions by enhancing efficacy, reducing toxicity, enabling targeted pain relief, and overcoming the limitations of current treatments. read more here.
Keywords: based formulations; vesicle based; treatment narrative; vesicle ... See more keywords
Long-Acting Extracellular Vesicle-Based Biologics in Osteoarthritis Immunotherapy
Sign Up to like & getrecommendations! Published in 2025 at "Bioengineering"
DOI: 10.3390/bioengineering12050525
Abstract: Osteoarthritis (OA) is a chronic degenerative joint disease characterized by low-grade inflammation, cartilage breakdown, and persistent pain. Despite its prevalence, current therapeutic strategies primarily focus on symptom management rather than modifying disease progression. Monoclonal antibodies… read more here.
Keywords: acting extracellular; long acting; based biologics; vesicle based ... See more keywords
Extracellular Vesicle-Based Hydrogels for Wound Healing Applications
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24044104
Abstract: Hydrogels and extracellular vesicle-based therapies have been proposed as emerging therapeutic assets in wound closure. The combination of these elements has given good results in managing chronic and acute wounds. The intrinsic characteristics of the… read more here.
Keywords: vesicle based; wound healing; extracellular vesicle; based hydrogels ... See more keywords
Extracellular Vesicle-Based Therapeutics: Preclinical and Clinical Investigations
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12121171
Abstract: Drug nanoformulations hold remarkable promise for the efficient delivery of therapeutics to a disease site. Unfortunately, artificial nanocarriers, mostly liposomes and polymeric nanoparticles, show limited applications due to the unfavorable pharmacokinetics and rapid clearance from… read more here.
Keywords: extracellular vesicle; vesicle based; therapeutics preclinical; clinical investigations ... See more keywords