Requirement of Cholesterol for Calcium‐Dependent Vesicle Fusion by Strengthening Synaptotagmin‐1‐Induced Membrane Bending (Adv. Sci. 15/2023)
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202206823
Abstract: Vesicle Fusion In article number 2206823, using the bottom‐up synthetic reconstitution, electron microscopy, and in‐vivo amperometry, Yongsoo Park and co‐workers show novel mechanisms of vesicle fusion triggered by calcium ions. Cholesterol stabilizes the local membrane… read more here.
Keywords: requirement cholesterol; fusion; vesicle fusion; membrane bending ... See more keywords
Synaptic vesicle fusion is modulated through feedback inhibition by dopamine auto‐receptors
Sign Up to like & getrecommendations! Published in 2019 at "Synapse"
DOI: 10.1002/syn.22131
Abstract: Mechanisms of synaptic vesicular fusion and neurotransmitter clearance are highly controlled processes whose finely‐tuned regulation is critical for neural function. This modulation has been suggested to involve pre‐synaptic auto‐receptors; however, their underlying mechanisms of action… read more here.
Keywords: auto; vesicle fusion; auto receptors; fusion ... See more keywords
SNARE-Mediated Single-Vesicle Fusion Events with Supported and Freestanding Lipid Membranes.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.04.032
Abstract: In vitro single-vesicle fusion assays are important tools to analyze the details of SNARE-mediated fusion processes. In this study, we employed planar pore-spanning membranes (PSMs) prepared on porous silicon substrates with large pore diameters of 5… read more here.
Keywords: single vesicle; snare mediated; vesicle fusion; vesicle ... See more keywords
MicroRNA exocytosis by large dense-core vesicle fusion
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep45661
Abstract: Neurotransmitters and peptide hormones are secreted into outside the cell by a vesicle fusion process. Although non-coding RNA (ncRNA) that include microRNA (miRNA) regulates gene expression inside the cell where they are transcribed, extracellular miRNA… read more here.
Keywords: vesicle fusion; vesicle; dense core; large dense ... See more keywords
Syntaxin-1A modulates vesicle fusion in mammalian neurons via juxtamembrane domain dependent palmitoylation of its transmembrane domain
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.03.11.483937
Abstract: SNAREs are undoubtedly one of the core elements of synaptic transmission. On the contrary to the well characterized function of their SNARE domains bringing the plasma and vesicular membranes together, the level of contribution of… read more here.
Keywords: jmd; domain; stx1a; vesicle fusion ... See more keywords
Endosomal vesicle fusion machinery is involved with the contractile vacuole in Dictyostelium discoideum.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cell science"
DOI: 10.1242/jcs.260477
Abstract: Contractile vacuoles (CVs) share common characteristics, such as a requirement for RAB11 and high levels of V-ATPase. These commonalities suggest a conserved evolutionary origin for the CVs with implications for understanding of the last common… read more here.
Keywords: endosomal vesicle; vesicle fusion; machinery; fusion machinery ... See more keywords
Vesicle Fusion as a Target Process for the Action of Sphingosine and Its Derived Drugs
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DOI: 10.3390/ijms23031086
Abstract: The fusion of membranes is a central part of the physiological processes involving the intracellular transport and maturation of vesicles and the final release of their contents, such as neurotransmitters and hormones, by exocytosis. Traditionally,… read more here.
Keywords: fusion; sphingosine derived; action; vesicle fusion ... See more keywords
Quantification of Giant Unilamellar Vesicle Fusion Products by High-Throughput Image Analysis
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24098241
Abstract: Artificial cells are based on dynamic compartmentalized systems. Thus, remodeling of membrane-bound systems, such as giant unilamellar vesicles, is finding applications beyond biological studies, to engineer cell-mimicking structures. Giant unilamellar vesicle fusion is rapidly becoming… read more here.
Keywords: fusion; fusion products; unilamellar vesicle; vesicle fusion ... See more keywords