The synaptic vesicle glycoprotein 2: structure, function, and disease relevance.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00351
Abstract: The synaptic vesicle glycoprotein 2 (SV2) family is comprised of three paralogs: SV2A, SV2B, and SV2C. In vertebrates, SV2s are 12-transmembrane proteins present on every secretory vesicle, including synaptic vesicles, and are critical to neurotransmission.… read more here.
Keywords: vesicle glycoprotein; disease; synaptic vesicle; function ... See more keywords
[18F]BIBD-181: A Novel Positron Emission Tomography Tracer Specific for Synaptic Vesicle Glycoprotein 2A.
Sign Up to like & getrecommendations! Published in 2022 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.2c00062
Abstract: Dysfunction or decreased expression of synaptic vesicle glycoprotein 2A (SV2A) is closely related to the progression of neurodegenerative diseases and psychiatric disorders. The development of positron emission tomography (PET) tracers targeting SV2A can provide a… read more here.
Keywords: 18f bibd; synaptic vesicle; positron emission; bibd 181 ... See more keywords
Brivaracetam attenuates pain behaviors in a murine model of neuropathic pain
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Pain"
DOI: 10.1177/1744806919886503
Abstract: Background The antiseizure racetams may provide novel molecular insights into neuropathic pain due to their unique mechanism involving synaptic vesicle glycoprotein 2A. Anti-allodynic effects of levetiracetam have been shown in animal models of neuropathic pain.… read more here.
Keywords: brivaracetam; vesicle glycoprotein; neuropathic pain; synaptic vesicle ... See more keywords