Vesicle trafficking in Arabidopsis pollen tubes.
Sign Up to like & getrecommendations! Published in 2022 at "FEBS letters"
DOI: 10.1002/1873-3468.14343
Abstract: The delivery of sperm cells via tip-growing pollen tubes is an innovation of seed plants and shows the importance of pollen tubes for reproduction as well as their specific growth kinetics. Fast-growing pollen tubes demand… read more here.
Keywords: pollen tubes; pollen; trafficking arabidopsis; arabidopsis pollen ... See more keywords
Integrated analysis based on vesicle trafficking-related genes identifying CNIH4 as a novel therapeutic target for glioma.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5947
Abstract: BACKGROUND Vesicle trafficking is a highly important process in numerous human diseases, especially in the central nervous system dysfunctions. However, as a key component of vesicle trafficking-related genes (VRGs), Cornichon family AMPA receptor auxiliary protein… read more here.
Keywords: trafficking related; analysis; vesicle trafficking; glioma ... See more keywords
Disparate genes come together: Spatial and genetic screens point to disruptions in vesicle trafficking and mRNA metabolism in synucleinopathies
Sign Up to like & getrecommendations! Published in 2017 at "Movement Disorders"
DOI: 10.1002/mds.26985
Abstract: a-Synuclein (asyn) is the primary component of proteinaceous aggregates that pathologically define a category of diseases termed synucleinopathies, which includes Parkinson’s disease (PD) and dementia with Lewy bodies. Elucidating the native function and pathway involvement… read more here.
Keywords: protein; disparate genes; spatial genetic; vesicle trafficking ... See more keywords
Proteomic identification of intracellular vesicle trafficking and protein glycosylation requirements for lumen inflation in Ciona notochord
Sign Up to like & getrecommendations! Published in 2023 at "PROTEOMICS"
DOI: 10.1002/pmic.202200460
Abstract: Lumen formation and inflation are crucial steps for tubular organ morphogenesis, yet the underling mechanism remains largely unrevealed. Here, we applied 4D proteomics to screen the lumenogenesis‐related proteins and revealed the biological pathways potentially that… read more here.
Keywords: lumen inflation; glycosylation; vesicle trafficking; lumen formation ... See more keywords
Amelioration of insulin resistance using the additive effect of ferulic acid and resveratrol on vesicle trafficking for skeletal muscle glucose metabolism
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6561
Abstract: Dysregulation of vesicle trafficking in muscle is one of the factors responsible for the pathogenesis of insulin resistance (IR). Ferulic acid (FER) and resveratrol (RSV) are known to have hypoglycemic property. In this study, differentiated… read more here.
Keywords: insulin; vesicle trafficking; muscle; effect ... See more keywords
Deregulation of autophagy and vesicle trafficking in Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.04.013
Abstract: Parkinson's disease (PD) is a common neurodegenerative disease characterized pathologically by the selective loss of dopaminergic neurons in the substantia nigra and the intracellular accumulation of α-synuclein in the Lewy bodies. While the pathogenic mechanisms… read more here.
Keywords: deregulation autophagy; vesicle trafficking; disease; parkinson disease ... See more keywords
C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia
Sign Up to like & getrecommendations! Published in 2017 at "Brain"
DOI: 10.1093/brain/awx024
Abstract: A non-coding hexanucleotide repeat expansion in intron 1 of the C9orf72 gene is the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia (C9ALS/FTD), however, the precise molecular mechanism by which the C9orf72 hexanucleotide… read more here.
Keywords: c9orf72 rab7l1; c9orf72; c9als ftd; vesicle trafficking ... See more keywords
ELMOD3-Rab1A-Flotillin2 cascade regulates lumen formation via vesicle trafficking in Ciona notochord
Sign Up to like & getrecommendations! Published in 2023 at "Open Biology"
DOI: 10.1098/rsob.220367
Abstract: Lumen development is a crucial phase in tubulogenesis, although its molecular mechanisms are largely unknown. In this study, we discovered an ELMO domain-containing 3 (ELMOD3), which belongs to ADP-ribosylation factor GTPase-activating protein family, was necessary… read more here.
Keywords: elmod3; vesicle trafficking; lumen formation; formation ... See more keywords
SCYL2 Genes Are Involved in Clathrin-Mediated Vesicle Trafficking and Essential for Plant Growth1[OPEN]
Sign Up to like & getrecommendations! Published in 2017 at "Plant Physiology"
DOI: 10.1104/pp.17.00824
Abstract: Vesicle membrane-associated SCYL2 proteins are vital for plant development. Protein transport between organelles is an essential process in all eukaryotic cells and is mediated by the regulation of processes such as vesicle formation, transport, docking,… read more here.
Keywords: essential plant; plant; vesicle; scyl2 genes ... See more keywords
Cytokine exocytosis and JAK/STAT activation in the Drosophila ovary requires the vesicle trafficking regulator α-Snap
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cell Science"
DOI: 10.1242/jcs.217638
Abstract: ABSTRACT How vesicle trafficking components actively contribute to regulation of paracrine signaling is unclear. We genetically uncovered a requirement for α-soluble NSF attachment protein (α-Snap) in the activation of the Janus kinase/signal transducer and activator… read more here.
Keywords: trafficking regulator; jak stat; vesicle trafficking;
An atypical Phytophthora sojae RxLR effector manipulates host vesicle trafficking to promote infection
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010104
Abstract: In plants, the apoplast is a critical battlefield for plant-microbe interactions. Plants secrete defense-related proteins into the apoplast to ward off the invasion of pathogens. How microbial pathogens overcome plant apoplastic immunity remains largely unknown.… read more here.
Keywords: rxlr effector; phytophthora sojae; vesicle trafficking;