Visualization of RIM-BP2’s crane-like function in neuronal vesicle transport using FRET
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DOI: 10.1038/s42003-025-08747-9
Abstract: “The last mile” of neuronal vesicles, from being tethered by the active zone filaments to docking at the presynaptic membrane, remains unclear, which limits the deep understanding of synaptic transmission and related physiological changes. Here,… read more here.
Keywords: rim bp2; bp2; membrane; vesicle transport ... See more keywords
Propofol attenuates kinesin-mediated axonal vesicle transport and fusion
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DOI: 10.1091/mbc.e22-07-0276
Abstract: Propofol is a widely used general anesthetic, yet the understanding of its cellular effects is fragmentary. General anesthetics are not as innocuous as once believed and have a wide range of molecular targets that include… read more here.
Keywords: vesicle transport; fusion; propofol; transport ... See more keywords
Kifunensine-sensitive ADP-ribosylation factor A1EG69R mutant revealed coordination of protein glycosylation and vesicle transport pathways.
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DOI: 10.1093/jxb/eraf017
Abstract: Complex N-glycans are asparagine (N)-linked branched sugar chains attached to secretory proteins in eukaryotes. They are produced by modification of N-linked oligosaccharide structures in the endoplasmic reticulum (ER) and Golgi apparatus. Complex N-glycans formed in… read more here.
Keywords: mutant; golgi apparatus; kifunensine sensitive; protein ... See more keywords
Neuroprogenitor Cells From Patients With TBCK Encephalopathy Suggest Deregulation of Early Secretory Vesicle Transport
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DOI: 10.3389/fncel.2021.803302
Abstract: Biallelic pathogenic variants in TBCK cause encephaloneuropathy, infantile hypotonia with psychomotor retardation, and characteristic facies 3 (IHPRF3). The molecular mechanisms underlying its neuronal phenotype are largely unexplored. In this study, we reported two sisters, who… read more here.
Keywords: vesicle transport; neuroprogenitor cells; transport; secretory ... See more keywords
Decoding the role of microtubules: a trafficking road for vesicle
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DOI: 10.7150/thno.110120
Abstract: Background: In eukaryotic cells, intracellular and extracellular vesicle transport systems are ubiquitous and tightly linked. This process involves well-defined initiation and termination points, as well as mechanisms for vesicle recycling. During transport, cytoskeletal components serve… read more here.
Keywords: decoding role; transport; microtubule; vesicle ... See more keywords