Alkylsulfones: novel chemical scaffolds targeting the vesicular acetylcholine transporter usher in a new generation of insecticides.
Sign Up to like & getrecommendations! Published in 2024 at "Pest management science"
DOI: 10.1002/ps.8462
Abstract: Insecticides targeting the nervous system have been the most widely used to control arthropod pests due to their fast onset of action leading to efficient crop protection. With their continued use, resistance has and will… read more here.
Keywords: vesicular acetylcholine; novel chemical; chemical scaffolds; acetylcholine transporter ... See more keywords
Reduced Vesicular Acetylcholine Transporter favors antidepressant behaviors and modulates serotonin and dopamine in female mouse brain
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.04.049
Abstract: &NA; Depression is extremely harmful to modern society. Despite its complex spectrum of symptoms, previous studies have mostly focused on the monaminergic system in search of pharmacological targets. However, other neurotransmitter systems have also been… read more here.
Keywords: acetylcholine transporter; vesicular acetylcholine; depressive like; serotonin dopamine ... See more keywords
In vitro characterization of [3H]VAT in cells, animal and human brain tissues for vesicular acetylcholine transporter.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174556
Abstract: Vesicular acetylcholine transporter plays a crucial role in the cholinergic system, and its alterations is implicated in several neurodegenerative disorders. We recently developed a PET imaging tracer [18F]VAT to target VAChT in vivo with high… read more here.
Keywords: acetylcholine transporter; vitro characterization; vesicular acetylcholine; vat ... See more keywords