WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-27344-y
Abstract: The sorting of soluble secretory proteins from the endoplasmic reticulum (ER) to the Golgi complex is mediated by coat protein complex II (COPII) vesicles and thought to required specific ER membrane cargo-receptor proteins. However, these… read more here.
Keywords: wfs1 functions; vesicular cargo; cargo; export vesicular ... See more keywords
Impact of mesenchymal stromal cell–derived vesicular cargo on B-cell acute lymphoblastic leukemia progression
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022007528
Abstract: Key Points • The PLEKHM1-associated endolysosomal system in MSCs affects BCR-ABL1+ B-ALL progression via release of extracellular vesicles.• B-ALL–derived inflammatory cytokines perpetuate this circuit in MSCs, modify vesicular cargo, and promote B-ALL cell signaling and… read more here.
Keywords: cell; mesenchymal stromal; progression; impact mesenchymal ... See more keywords