Temporal Dynamics of Cortical Microinfarcts in Cerebral Small Vessel Disease.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2019.5106
Abstract: Importance Neuropathology studies show a high prevalence of cortical microinfarcts (CMIs) in aging individuals, especially in patients with cerebrovascular disease and dementia. However, most, are invisible on T1- and T2-weighted magnetic resonance imaging (MRI), raising… read more here.
Keywords: cerebral small; cmi; small vessel; cortical microinfarcts ... See more keywords
Framework for Clinical Trials in Cerebral Small Vessel Disease (FINESSE): A Review.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.2262
Abstract: Importance Cerebral small vessel disease (SVD) causes a quarter of strokes and is the most common pathology underlying vascular cognitive impairment and dementia. An important step to developing new treatments is better trial methodology. Disease… read more here.
Keywords: vessel disease; clinical trials; methodology; cerebral small ... See more keywords
Predictors of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2022.4038
Abstract: This prespecified analysis of the Stroke of Known Cause and Underlying Atrial Fibrillation (STROKE AF) randomized clinical trial investigates the association of commonly assessed risk factors with undiagnosed atrial fibrillation in patients with ischemic stroke… read more here.
Keywords: fibrillation patients; vessel disease; fibrillation; small vessel ... See more keywords
Contribution of acute infarcts to cerebral small vessel disease progression
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DOI: 10.1002/ana.25556
Abstract: To determine the contribution of acute infarcts, evidenced by diffusionâweighted imaging positive (DWI+) lesions, to progression of white matter hyperintensities (WMH) and other cerebral small vessel disease (SVD) markers. read more here.
Keywords: cerebral small; contribution acute; small vessel; acute infarcts ... See more keywords
Are neuropsychiatric symptoms a marker of small vessel disease progression in older adults? Evidence from the Lothian Birth Cohort 1936
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5855
Abstract: Neuropsychiatric symptoms could form part of an early cerebral small vessel disease prodrome that is detectable before stroke or dementia onset. We aimed to identify whether apathy, depression, anxiety, and subjective memory complaints associate with… read more here.
Keywords: neuropsychiatric symptoms; vessel disease; symptoms marker; small vessel ... See more keywords
Cerebral Microbleeds Are Associated With Increased Brain Iron and Cognitive Impairment in Patients With Cerebral Small Vessel Disease: A Quantitative Susceptibility Mapping Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28092
Abstract: Cerebral microbleeds (CMBs) have been recognized to play an important role in cognitive impairment of cerebral small vessel disease (CSVD) patients. However, the mechanism of this effect is still unclear. read more here.
Keywords: cerebral microbleeds; vessel disease; cerebral small; small vessel ... See more keywords
Report of two pedigrees with heterozygous HTRA1 variantsârelated cerebral small vessel disease and literature review
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DOI: 10.1002/mgg3.2032
Abstract: Biallelic HTRA1 pathogenic variants are associated with autosomal recessive cerebral arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL). Recent studies have indicated that heterozygous HTRA1 variants are related to autosomal dominant hereditary cerebral small vessel disease… read more here.
Keywords: variants related; heterozygous htra1; vessel disease; htra1 variants ... See more keywords
Cerebral small vessel disease burden and functional and radiographic outcomes in intracerebral hemorrhage
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DOI: 10.1007/s00415-018-9059-5
Abstract: ObjectiveTo examine the effect of individual cerebral small vessel disease (CSVD) markers and cumulative CSVD burden on functional independence, ambulation and hematoma expansion in spontaneous intracerebral hemorrhage (ICH).MethodsRetrospective analysis of prospectively collected data from an… read more here.
Keywords: cerebral small; ambulation; csvd; small vessel ... See more keywords
Effect of small-vessel disease on cognitive trajectory after atrial fibrillation-related ischaemic stroke or TIA
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DOI: 10.1007/s00415-019-09256-6
Abstract: Post-stroke dementia is common but has heterogenous mechanisms that are not fully understood, particularly in patients with atrial fibrillation (AF)-related ischaemic stroke or TIA. We investigated the relationship between MRI small-vessel disease markers (including a… read more here.
Keywords: small vessel; ischaemic stroke; vessel disease;
Small vessel disease and collaterals in ischemic stroke patients treated with thrombectomy
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DOI: 10.1007/s00415-022-11099-7
Abstract: To determine the influence of the cerebral small vessel disease (SVD) burden on collateral recruitment in patients treated with mechanical thrombectomy (MT) for anterior circulation acute ischemic stroke (AIS). Patients with AIS due to large… read more here.
Keywords: patients treated; ischemic stroke; vessel disease; radiology ... See more keywords
Cerebrovascular disease: Neuroimaging of cerebral small vessel disease.
Sign Up to like & getrecommendations! Published in 2019 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2019.07.008
Abstract: The cerebral microvasculature is exceptionally vulnerable to changes due to aging. Both the radiological and clinical manifestations of cerebral small vessel disease (cSVD) in older age are highly heterogeneous, ranging from no symptomatology to devastating… read more here.
Keywords: cerebral small; csvd; disease; small vessel ... See more keywords