LINC00657 activates PD-L1 to promote osteosarcoma metastasis via miR-106a.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.29574
Abstract: Osteosarcoma (OS) cells are one of the primary cancer-related causes of death around the world. Long noncoding RNAs are key for OS progression; however, the detailed molecular mechanism remains unknown. LINC00657, miR-106a, and programmed death… read more here.
Keywords: linc00657; metastasis; vessel formation; linc00657 activates ... See more keywords
Construction of vascularized tissue-engineered bone with a double-cell sheet complex.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.07.024
Abstract: A double-cell sheet (DCS) complex composed of an osteogenic cell sheet and a vascular endothelial cell sheet with osteogenesis and blood vessel formation potential was developed in this study. The osteogenic and vascular endothelial cell… read more here.
Keywords: dcs; blood vessel; vessel formation; cell sheet ... See more keywords
Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription
Sign Up to like & getrecommendations! Published in 2018 at "Cell Discovery"
DOI: 10.1038/s41421-018-0024-3
Abstract: PEAK1 is a newly described tyrosine kinase and scaffold protein that transmits integrin-mediated extracellular matrix (ECM) signals to facilitate cell movement and growth. While aberrant expression of PEAK1 has been linked to cancer progression, its… read more here.
Keywords: transcription; peak1; kinase; vessel formation ... See more keywords
Seasonal patterns of increases in stem girth, vessel development, and hydraulic function in deciduous tree species.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of botany"
DOI: 10.1093/aob/mcac032
Abstract: BACKGROUND AND AIMS The onset of spring growth and vessel formation were examined within three deciduous woody plant species, Acer rubrum, Populus balsamifera spp. trichocarpa, and Quercus rubra. We were broadly interested in the lag… read more here.
Keywords: expansion; vessel formation; function; seasonal patterns ... See more keywords
Mechanisms of new blood vessel formation and proliferative heterogeneity of endothelial cells.
Sign Up to like & getrecommendations! Published in 2020 at "International immunology"
DOI: 10.1093/intimm/dxaa008
Abstract: The vast blood vessel network of the circulatory system is crucial for maintaining bodily homeostasis, delivering essential molecules and blood cells, and removing waste products. Blood vessel dysfunction and dysregulation of new blood-vessel formation are… read more here.
Keywords: new blood; blood vessel; vessel; vessel formation ... See more keywords
An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation
Sign Up to like & getrecommendations! Published in 2017 at "Circulation Research"
DOI: 10.1161/circresaha.116.308813
Abstract: Rationale: Lymphatic vessel formation and function constitutes a physiologically and pathophysiologically important process, but its genetic control is not well understood. Objective: Here, we identify the secreted Polydom/Svep1 protein as essential for the formation of… read more here.
Keywords: polydom svep1; polydom; vessel formation; lymphatic vessel ... See more keywords
Region-specific astrogliosis: differential vessel formation contributes to different patterns of astrogliosis in the cortex and striatum
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Brain"
DOI: 10.1186/s13041-020-00642-0
Abstract: Brain injury causes astrocytes to become reactive (astrogliosis). In this study, we compared astrogliosis in acutely injured cortex and striatum of adult FVB/N mice induced by stereotaxic injection of ATP, a component of danger-associated molecular… read more here.
Keywords: cortex; striatum; astrogliosis; formation ... See more keywords
Cellular heterogeneity and stem cells of vascular endothelial cells in blood vessel formation and homeostasis: Insights from single-cell RNA sequencing
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1146399
Abstract: Vascular endothelial cells (ECs) that constitute the inner surface of blood vessels are essential for new vessel formation and organ homeostasis. ECs display remarkable phenotypic heterogeneity across different organs and the vascular tree during angiogenesis… read more here.
Keywords: heterogeneity; scrna seq; vessel formation; homeostasis ... See more keywords
Caveolin-1 Promoted Collateral Vessel Formation in Patients With Moyamoya Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.796339
Abstract: Background Caveolin-1 (Cav-1) plays pivotal roles in the endothelial function and angiogenesis postischemia. Moyamoya disease (MMD) is characterized by progressive artery stenosis with unknown etiology. We aim to determine whether serum Cav-1 levels of patients… read more here.
Keywords: patients mmd; collateral vessel; vessel formation; moyamoya disease ... See more keywords
Angiogenesis and Functional Vessel Formation Induced by Interstitial Flow and Vascular Endothelial Growth Factor Using a Microfluidic Chip
Sign Up to like & getrecommendations! Published in 2022 at "Micromachines"
DOI: 10.3390/mi13020225
Abstract: Angiogenesis occurs during both physiological and pathological processes. In this study, a microfluidic chip for the development of angiogenesis was utilized to assess angiogenic sprouting and functional vessel formation. We also found that vascular endothelial… read more here.
Keywords: angiogenesis; functional vessel; vessel formation; chip ... See more keywords
Total flavonoids of Rhizoma Drynariae enhances CD31hiEmcnhi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF-BB/VEGF/RUNX2/OSX signaling axis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2022.5167
Abstract: Total flavonoids of Rhizoma Drynariae (TFRD), extracted from the kidney-tonifying Traditional Chinese medicine Rhizoma Drynariae, can be effective in treating osteoporosis, bone fractures and defects. However, the pharmacological effects of TFRD on the specific vessel… read more here.
Keywords: bone; vessel formation; pdgf vegf; formation ... See more keywords