Effect and Mechanism of BDNF/TrkB Signaling on Vestibular Compensation.
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DOI: 10.1080/21655979.2021.1997565
Abstract: Brain-derived neurotrophic factor (BDNF) regulates neuronal plasticity by targeting the tyrosine kinase B receptor (TrkB) receptor, but limited researches concentrate on the role of BDNF/TrkB signaling in vestibular compensation. In this study, rats with unilateral… read more here.
Keywords: bdnf trkb; trkb signaling; vestibular compensation; trkb ... See more keywords
MicroRNA‐219a‐5p−mediated inhibition of CaMKIIγ facilitates vestibular compensation in acute vertigo by promoting protein kinase C expression
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DOI: 10.1111/nyas.14376
Abstract: Vestibular compensation (VC) refers to a behavioral recovery process in which firing rates of bilateral vestibular nuclei neurons are rebalanced. Our study aimed to investigate the underlying mechanism by which miR‐219a‐5p regulates Ca2+/calmodulin–dependent protein kinase… read more here.
Keywords: vestibular compensation; mir 219a; acute vertigo; camkii ... See more keywords
Head-shaking-induced nystagmus reflects dynamic vestibular compensation: A 2-year follow-up study
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DOI: 10.3389/fneur.2022.949696
Abstract: Purpose We aimed to assess the ability of a head-shaking test (HST) to reflect vestibular compensation in patients after unilateral peripheral vestibular loss and to provide missing evidence and new insights into the features of… read more here.
Keywords: head shaking; head; vestibular compensation; hsn ... See more keywords
Vertigoheel improves central vestibular compensation after unilateral peripheral vestibulopathy in rats
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DOI: 10.3389/fneur.2022.969047
Abstract: The aim of this study was to assess the effect of Vertigoheel on central vestibular compensation and cognitive deficits in rats subjected to peripheral vestibular loss. Young adult male Long Evans rats were subjected to… read more here.
Keywords: central vestibular; vertigoheel; vestibular compensation; vehicle ... See more keywords
Effects of Betahistine on the Development of Vestibular Compensation after Unilateral Labyrinthectomy in Rats
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DOI: 10.3390/brainsci11030360
Abstract: Background: Vestibular compensation (VC) after unilateral labyrinthectomy (UL) consists of the initial and late processes. These processes can be evaluated based on the decline in the frequency of spontaneous nystagmus (SN) and the number of… read more here.
Keywords: compensation unilateral; vestibular compensation; effects betahistine; unilateral labyrinthectomy ... See more keywords