Abstract 6377: TEAD-targeting small molecules induce a cofactor switch to regulate the Hippo pathway
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DOI: 10.1158/1538-7445.am2025-6377
Abstract: The Hippo signaling pathway is a major regulator of cellular growth and is frequently deregulated in cancer. TEAD proteins are the main transcriptional effectors of the Hippo pathway and a pharmacological target in oncology. Most… read more here.
Keywords: hippo pathway; tead; tead targeting; vgll4 ... See more keywords