VHL and Hypoxia Signaling: Beyond HIF in Cancer
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DOI: 10.3390/biomedicines6010035
Abstract: Von Hippel-Lindau (VHL) is an important tumor suppressor that is lost in the majority of clear cell carcinoma of renal cancer (ccRCC). Its regulatory pathway involves the activity of E3 ligase, which targets hypoxia inducible… read more here.
Keywords: hypoxia signaling; vhl; signaling beyond; vhl hypoxia ... See more keywords