Rivastigmine ameliorates indomethacin experimentally induced gastric mucosal injury via activating α7nAChR with inhibiting oxidative stress and apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23147
Abstract: The current study aimed to investigate the potential ameliorative role of Rivastigmine (RIVA), the anti‐Alzheimer drug, against the gastric mucosal injury caused by indomethacin (IND). The rats were divided into four groups: group I was… read more here.
Keywords: injury via; gastric mucosal; via activating; induced gastric ... See more keywords
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicity Research"
DOI: 10.1007/s12640-019-00148-1
Abstract: Paraquat (PQ), a widely characterized neurotoxicant, has been generally accepted as one of the environmental factors in the etiology of Parkinson’s disease (PD). Despite the direct evidence that PQ could induce inflammatory responses in central… read more here.
Keywords: neuroinflammatory responses; activating rage; via activating; signaling pathway ... See more keywords
Tenuigenin inhibits LPS‐induced inflammatory responses in microglia via activating the Nrf2‐mediated HO‐1 signaling pathway
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.05.004
Abstract: &NA; Tenuigenin (TGN), a major active component of polygala tenuifolia root, has been reported to have anti‐inflammatory effect. In this study, we investigated the anti‐neuroinflammatory effects of TGN on LPS‐induced inflammation both in vitro and… read more here.
Keywords: inflammatory responses; via activating; responses microglia; lps induced ... See more keywords
Chemopreventive effects of atractylenolide II on mammary tumorigenesis via activating Nrf2-ARE pathway
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.20546
Abstract: In the studies of chemoprevention, the Nrf2-ARE signaling pathway has received widespread attention due to its anti-inflammatory and anti-oxidation effects. Our previous study indicated that atractylenolide II, which is an active component of Atractylodes macrocephala… read more here.
Keywords: via activating; nrf2 pathway; nrf2 signaling; mammary tumorigenesis ... See more keywords
M2-like Macrophages-derived CCL17 Promotes Esophageal Squamous Cell Carcinoma Metastasis and Stemness via Activating CCR4-mediated ERK/PD-L1 Pathway.
Sign Up to like & getrecommendations! Published in 2024 at "Current molecular medicine"
DOI: 10.2174/0115665240312877241010123403
Abstract: BACKGROUND AND OBJECTIVE High morbidity, high mortality and poor prognosis of esophageal squamous cell carcinoma (ESCC) highlights the urgent need for novel therapeutic strategies against ESCC. The current study addresses the precise role of M2-like… read more here.
Keywords: activating ccr4; macrophages derived; like macrophages; via activating ... See more keywords
Eye Drops of Metformin Prevents Fibrosis After Glaucoma Filtration Surgery in Rats via Activating AMPK/Nrf2 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.01038
Abstract: Metformin has effective therapeutic effects in anti-tumor and anti-fibrotic diseases. However, how the antifibrotic effect of metformin in the eye and how it is transferred are still unclear. Here, the eye drop of metformin treatment… read more here.
Keywords: via activating; surgery; fibrosis; activating ampk ... See more keywords