Articles with "via adrenoceptors" as a keyword



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Bidirectional modulation of TNF-α transcription via α- and β-adrenoceptors in cultured astrocytes from rat spinal cord.

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Published in 2020 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2020.05.011

Abstract: Noradrenaline (NA) suppresses TNF-α production via β-adrenoceptors (ARs) in brain astrocytes. However, the downstream pathways from β-ARs, and the involvement of α-ARs, remains unknown. In this study, we investigated the AR-mediated regulation of TNF-α mRNA… read more here.

Keywords: astrocytes rat; tnf; via adrenoceptors; cultured astrocytes ... See more keywords
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Noradrenaline increases intracellular Ca2+ concentration in epithelial cells via α2-adrenoceptors in isolated mouse ileal crypts.

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Published in 2022 at "Journal of pharmacological sciences"

DOI: 10.1016/j.jphs.2022.01.010

Abstract: The stimulation of α2-adrenoceptors caused a transient increase of intracellular calcium concentration ([Ca2+]i) monitored by ratiometry using Fura-2 in epithelial cells including enterochromaffin cells in isolated mouse ileal crypts, while stimulation of α1-and β-adrenoceptors had… read more here.

Keywords: mouse ileal; isolated mouse; concentration; ileal crypts ... See more keywords
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Dexmedetomidine Inhibits Voltage-Gated Sodium Channels via α2-Adrenoceptors in Trigeminal Ganglion Neurons

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Published in 2018 at "Mediators of Inflammation"

DOI: 10.1155/2018/1782719

Abstract: Dexmedetomidine, an α2-adrenoceptor agonist, is widely used as a sedative and analgesic agent in a number of clinical applications. However, little is known about the mechanism by which it exerts its analgesic effects on the… read more here.

Keywords: voltage gated; via adrenoceptors; gated sodium; sodium channels ... See more keywords