Trifluoromethylation via broken C-F bonds.
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DOI: 10.1126/science.356.6344.1243-r
Abstract: Chemistry Trifluoromethyl substituents are widely used in pharmaceutical research to tune the properties of drug candidates. Generally, they are introduced intact through the formation of carbon-carbon bonds. Levin et al. discovered an unusual alternative mechanism,… read more here.
Keywords: carbon; science; trifluoromethylation via; chemistry ... See more keywords