MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping
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DOI: 10.1038/ni.3812
Abstract: MLL4 is an essential subunit of the histone H3 Lys4 (H3K4)-methylation complexes. We found that MLL4 deficiency compromised the development of regulatory T cells (Treg cells) and resulted in a substantial decrease in monomethylated H3K4… read more here.
Keywords: via chromatin; chromatin; chromatin looping; mll4 ... See more keywords