A rapid entry into thioflavanones via conjugate additions of diarylcuprates to thiochromones
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DOI: 10.1016/j.tet.2017.08.012
Abstract: Abstract Thiochromone undergo conjugate addition reactions with arylcuprates to afford 2-substituted thioflavanones, providing an efficient synthetic approach to privileged sulfur-containing structural motifs and valuable precursor for many pharmaceuticals. Excellent yields of substituted thioflavanones are achieved… read more here.
Keywords: rapid entry; entry thioflavanones; conjugate; via conjugate ... See more keywords
Diastereoselective Synthesis of γ-Lactams and δ-Lactams via a Conjugate Addition-Initiated Tandem Reaction
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DOI: 10.1055/s-0037-1611552
Abstract: β-Alkoxycarbonyl-γ-lactams and γ-alkoxycarbonyl-δ-lactams were synthesized via a conjugate alkylation/Mannich reaction/lactamization tandem reaction of unsaturated dicarboxylates with diethyl zinc and aldimines. The high yield, the ready availability of the reagents, and especially the high diastereoselectivity are… read more here.
Keywords: tandem reaction; diastereoselective synthesis; synthesis lactams; via conjugate ... See more keywords