A β-glucan from Grifola frondosa effectively delivers therapeutic oligonucleotide into cells via dectin-1 receptor and attenuates TNFα gene expression.
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DOI: 10.1016/j.ijbiomac.2020.01.236
Abstract: Grifola frondosa is an edible and medicinal mushroom with great nutritional values and bioactivities. In the present study, a soluble homogeneous β-glucan, GFPS, with high molecular mass of 5.42 × 106 Da was purified from the fruit bodies… read more here.
Keywords: via dectin; grifola frondosa; gfps; cells via ... See more keywords