Cannabidiol induces autophagy via ERK1/2 activation in neural cells
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DOI: 10.1038/s41598-021-84879-2
Abstract: Autophagy is a lysosomal catabolic process essential to cell homeostasis and is related to the neuroprotection of the central nervous system. Cannabidiol (CBD) is a non-psychotropic phytocannabinoid present in Cannabis sativa. Many therapeutic actions have… read more here.
Keywords: autophagy via; erk1 activation; induces autophagy; cannabidiol induces ... See more keywords
17β-Estradiol Enhances Schwann Cell Differentiation via the ERβ-ERK1/2 Signaling Pathway and Promotes Remyelination in Injured Sciatic Nerves
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DOI: 10.3389/fphar.2018.01026
Abstract: Remyelination is critical for nerve regeneration. However, the molecular mechanism involved in remyelination is poorly understood. To explore the roles of 17β-estradiol (E2) for myelination in the peripheral nervous system, we used a co-culture model… read more here.
Keywords: promotes remyelination; differentiation; sciatic nerves; erk1 signaling ... See more keywords
Coxsackieviruses B3 infection of myocardial microvascular endothelial cells activates fractalkine via the ERK1/2 signaling pathway
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DOI: 10.3892/mmr.2017.7536
Abstract: Infections by pathogens may lead to cardiovascular diseases, including acute/chronic myocarditis. (Coxsackieviruses B3) CVB3 is considered to be the most common causative agent in m-yocarditis, which can lead to dilated cardiomyopathy. The present study aimed… read more here.
Keywords: myocardial microvascular; signaling pathway; microvascular endothelial; endothelial cells ... See more keywords