Perfluorooctane sulfonate aggravates CCl4‐induced hepatic fibrosis via HMGB1/TLR4/Smad signaling
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23458
Abstract: Perfluorooctane sulfonate (PFOS) is a widespread environmental pollutant and may cause a variety of adverse health effects. The hepatotoxicity of PFOS has attracted particular attention, given the fact that the liver has one of the… read more here.
Keywords: pfos; tlr4; pfos exposure; via hmgb1 ... See more keywords
Anti-depressive effect of arctiin by attenuating neuroinflammation via HMGB1/TLR4- and TNF-α/TNFR1-mediated NF-κB activation.
Sign Up to like & getrecommendations! Published in 2020 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.0c00120
Abstract: Inflammation is a potential factor in the pathophysiology of depression. A traditional Chinese herbal medicine, arctiin, and its aglycone, arctigenin, are the major bioactive components in Fructus arctii and exhibit neuroprotective and anti-inflammatory activities. Arctigenin… read more here.
Keywords: arctiin; tnf; activation; via hmgb1 ... See more keywords