Site-selective functionalization of remote aliphatic C–H bonds via C–H metallation
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DOI: 10.1039/d0sc05944g
Abstract: Directing group assistance provided a paradigm for controlling site-selectivity in transition metal-catalyzed C–H functionalization reactions. However, the kinetically and thermodynamically favored formation of 5-membered metallacycles has greatly hampered the selective activation of remote C(sp3)–H bonds… read more here.
Keywords: via metallation; selective functionalization; functionalization remote; bonds via ... See more keywords