PARP inhibition by olaparib alleviates chronic asthma‐associated remodeling features via modulating inflammasome signaling in mice
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.2048
Abstract: Despite the reported role of poly(ADP‐ribose) polymerase (PARP) in asthma inflammation, its contribution during remodeling is not clearly known. The main aim of the current investigation was to examine the potential of olaparib, a pharmacological… read more here.
Keywords: olaparib; via modulating; inflammasome signaling; chronic asthma ... See more keywords
N-Acetylcysteine extends lifespan of Drosophila via modulating ROS scavenger gene expression
Sign Up to like & getrecommendations! Published in 2019 at "Biogerontology"
DOI: 10.1007/s10522-019-09815-4
Abstract: N-Acetylcysteine (NAc) has been shown to play a diversity of favorable health-related roles (e.g., antioxidant, paracetamol antidote, mucolytics, neuroprotective agent). Having said that, here in this study, we evaluate the health-promoting properties of NAc, particularly… read more here.
Keywords: drosophila; extends lifespan; via modulating; acetylcysteine extends ... See more keywords
Controlling the mechanical properties of hydrogels via modulating the side-chain length.
Sign Up to like & getrecommendations! Published in 2023 at "Soft matter"
DOI: 10.1039/d3sm00134b
Abstract: Even though the toughness of hydrogels is usually adjusted by changing the cross-linking density and structure, or the polymer concentration, we have discovered a new strategy to control the toughness via modulating the side-chain length.… read more here.
Keywords: side chain; side; modulating side; via modulating ... See more keywords
Myrcene exerts anti-asthmatic activity in neonatal rats via modulating the matrix remodeling
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/2058738420954948
Abstract: Myrcene (MC), an organic hydrocarbon, was found to exert anti-inflammatory, analgesic, antimutagenic and antioxidant properties. However, the protective role of MC has not been reported against neonatal asthma. Wistar rats induced with asthma were administered… read more here.
Keywords: anti asthmatic; myrcene; via modulating; matrix ... See more keywords
MiR-543 promotes tumorigenesis and angiogenesis in non-small cell lung cancer via modulating metastasis associated protein 1
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DOI: 10.1186/s10020-020-00175-1
Abstract: Objective This study is aimed to explore the role of miR-543 in non-small cell lung cancer (NSCLC), and verify whether miR-543 targets metastasis associated protein 1 (MTA1) to affect tumorigenesis and angiogenesis in NSCLC. Methods… read more here.
Keywords: tumorigenesis angiogenesis; nsclc; via modulating; mir ... See more keywords
CsWRKY25 Improves Resistance of Citrus Fruit to Penicillium digitatum via Modulating Reactive Oxygen Species Production
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2021.818198
Abstract: WRKY transcription factors (TFs) play crucial roles in the regulation of biotic stress. Citrus is the most productive fruit in the world. It is of great value to investigate the regulatory molecular mechanism of WRKYs… read more here.
Keywords: digitatum via; resistance; via modulating; citrus ... See more keywords