Cannabidiol Protects Human Skin Keratinocytes from Hydrogen-Peroxide-Induced Oxidative Stress via Modulation of the Caspase-1-IL-1β Axis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.1c00083
Abstract: Preclinical and clinical studies support cannabidiol (CBD)'s antioxidant and anti-inflammatory effects, which are linked to its skin protective effects, but there have been limited mechanistic studies reported. Herein we evaluated CBD's protective effects against hydrogen… read more here.
Keywords: caspase; hydrogen peroxide; via modulation; induced oxidative ... See more keywords
Band-structure Tunability via Modulation of Excitons in Semiconductor Nanostructures: Manifestation in Photocatalytic Fuel Generation
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d3nr02116e
Abstract: Understanding the energetics of electron transfer at semiconductors interface is crucial for the development of solar harvesting technologies, including photovoltaics, photocatalysis and solar fuel systems. However, the modern artificial photosynthetic... read more here.
Keywords: modulation excitons; fuel; tunability via; structure tunability ... See more keywords
Electroacupuncture exerts an anti-migraine effect via modulation of the 5-HT7 receptor in the conscious rat
Sign Up to like & getrecommendations! Published in 2019 at "Acupuncture in Medicine"
DOI: 10.1136/acupmed-2017-011410
Abstract: Background: Acupuncture has been recommended as an alternative therapy for migraine. Emerging evidence suggests that the 5-HT7 receptor (5-HT7R) plays a significant facilitatory role in descending modulation in migraine pathophysiology, and that activation of 5-HT7R… read more here.
Keywords: modulation; ht7 receptor; migraine; via modulation ... See more keywords
7α,25-Dihydroxycholesterol-Induced Oxiapoptophagic Chondrocyte Death via the Modulation of p53-Akt-mTOR Axis in Osteoarthritis Pathogenesis
Sign Up to like & getrecommendations! Published in 2023 at "Molecules and Cells"
DOI: 10.14348/molcells.2023.2149
Abstract: This study aimed to exploring the pathophysiological mechanism of 7α,25-dihydroxycholesterol (7α,25-DHC) in osteoarthritis (OA) pathogenesis. 7α,25-DHC accelerated the proteoglycan loss in ex vivo organ-cultured articular cartilage explant. It was mediated by the decreasing extracellular matrix… read more here.
Keywords: osteoarthritis pathogenesis; chondrocyte death; via modulation; death via ... See more keywords
Anti-diabetic Effects of Macronutrients via Modulation of Angiogenesis: A Comprehensive Review on Carbohydrates and Proteins.
Sign Up to like & getrecommendations! Published in 2022 at "Current molecular medicine"
DOI: 10.2174/1566524022666220321125548
Abstract: BACKGROUND Diabetes is a major global health concern, manifesting the symptoms of chronic hyperglycemia. Either insufficient or excessive angiogenesis is generally involved in the pathogenesis of diabetes and its complications. OBJECTIVE Given that macronutrients are… read more here.
Keywords: modulation angiogenesis; effects macronutrients; angiogenesis; carbohydrates proteins ... See more keywords
Punicalagin Regulates Apoptosis-Autophagy Switch via Modulation of Annexin A1 in Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Nutrients"
DOI: 10.3390/nu12082430
Abstract: Punicalagin (PU), a polyphenol extracted from pomegranate (Punica granatum) husk is proven to have anti-cancer effects on different types of cancer including colorectal cancer (CRC). Its role in modulating endogenous protein as a means of… read more here.
Keywords: cancer; apoptosis autophagy; colorectal cancer; via modulation ... See more keywords
Administration of Bifidobacterium breve Improves the Brain Function of Aβ1-42-Treated Mice via the Modulation of the Gut Microbiome
Sign Up to like & getrecommendations! Published in 2021 at "Nutrients"
DOI: 10.3390/nu13051602
Abstract: Psychobiotics are used to treat neurological disorders, including mild cognitive impairment (MCI) and Alzheimer’s disease (AD). However, the mechanisms underlying their neuroprotective effects remain unclear. Herein, we report that the administration of bifidobacteria in an… read more here.
Keywords: administration; modulation gut; bifidobacterium breve; via modulation ... See more keywords
Co-Treatment with Human Leukocyte Extract and Albendazole Stimulates Drug’s Efficacy and Th1 Biased Immune Response in Mesocestoides vogae (Cestoda) Infection via Modulation of Transcription Factors, Macrophage Polarization, and Cytokine Profiles
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15020541
Abstract: The model flatworm Mesocestoides vogae proliferating stage of infection elicits immunosuppression in the host. It was used to investigate the effects of human leukocyte extract (DLE) alone and in combination with anthelmintic albendazole (ABZ) on… read more here.
Keywords: leukocyte extract; infection; via modulation; human leukocyte ... See more keywords