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Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200246
Abstract: Local anesthetics occupy a prime position in clinical medicine as they temporarily relieve the pain by blocking voltageāgated sodium channels. However, limited structural diversity, problems with the efficiency of syntheses and increasing toxicity, mean that…
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Keywords:
multicomponent reactions;
methodology;
local anesthetics;
via multicomponent ... See more keywords
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1
Published in 2017 at "Superlattices and Microstructures"
DOI: 10.1016/j.spmi.2017.11.025
Abstract: Abstract A quintessential perspective for elaborating the pivotal role of quinary chalogenides such as CZTSSe plunges the thrust for exploration of non-vacuum approach for development of multicomponent chalcogenides utilizing organic surfactants and solvents for the…
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Keywords:
cztse czts;
via multicomponent;
czts via;
multicomponent ... See more keywords
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Published in 2019 at "ACS Catalysis"
DOI: 10.1021/acscatal.9b00581
Abstract: A one-pot, four-component Pd-catalyzed coupling has been developed for the synthesis of unsymmetrical 1,2-diketones from aryl halides and alkyl zincs employing tert-butyl isocyanide as a CO source. The intermediate 1,2-diketones have been elaborated to quinoxalines.…
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Keywords:
synthesis;
synthesis diketones;
diketones via;
via multicomponent ... See more keywords
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2
Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c11071
Abstract: Multicomponent reactions (MCRs) combine at least three reactants to afford the desired product in a highly atom-economic way and are therefore viewed as efficient one-pot combinatorial synthesis tools allowing one to significantly boost molecular complexity…
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Keywords:
multicomponent reactions;
organic frameworks;
construction covalent;
via multicomponent ... See more keywords