Asymmetric Hydroarylation of Enones via Nickel-Catalyzed 5-Endo-Trig Cyclization.
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DOI: 10.1021/acs.orglett.9b02130
Abstract: A nickel-catalyzed reductive cyclization of enones affords a wide array of indanones in high enantiomeric induction. The reaction is featured with an unprecedented broad scope of substrates. The versatility of the new method is demonstrated… read more here.
Keywords: hydroarylation enones; enones via; asymmetric hydroarylation; cyclization ... See more keywords
Total Synthesis of Indolizidine Alkaloids via Nickel-Catalyzed (4 + 2) Cyclization.
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DOI: 10.1021/acs.orglett.9b04479
Abstract: A Ni-catalyzed (4 + 2) cycloaddition of alkynes and azetidinones toward piperidinones was used as key reaction in the enantioselective synthesis of naturally occurring indolizidine alkaloids. The reaction benefits from the use of an easily… read more here.
Keywords: synthesis indolizidine; total synthesis; alkaloids via; indolizidine alkaloids ... See more keywords
Deoxygenation of Ethers To Form Carbon-Carbon Bonds via Nickel Catalysis.
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DOI: 10.1021/jacs.7b02326
Abstract: In this article a successful protocol was developed to construct carbon-carbon bonds by the extrusion of the O atom of ethers via nickel catalysis in the presence of reductants. This methodology is featured as a… read more here.
Keywords: carbon bonds; nickel catalysis; carbon; carbon carbon ... See more keywords
Synthesis of 1,4-enynes via nickel-catalyzed cross-coupling of allylic alcohols with alkynylzinc reagents.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc05221g
Abstract: Synthesis of 1,4-enynes was performed via nickel-catalyzed cross-coupling of allylic alcohols with alkynylzinc reagents. The reaction features high regio- and E/Z-selectivity when aryl-substituted allylic alcohols were employed. The method also exhibits a wide scope of… read more here.
Keywords: synthesis enynes; allylic alcohols; cross coupling; catalyzed cross ... See more keywords