LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "via nlrp3" as a keyword



Photo from wikipedia

Monocytes promote pyroptosis of endothelial cells during lung ischemia-reperfusion via IL-1R/NF-κB/NLRP3 signaling.

Sign Up to like & get
recommendations! Published in 2021 at "Life sciences"

DOI: 10.1016/j.lfs.2021.119402

Abstract: In our previous study, we observed that donor pulmonary intravascular nonclassical monocytes play a major role in early PGF, but the specific mechanism remained unclear. In this study, we investigated the mechanistic role of monocytes… read more here.

Keywords: via nlrp3; pyroptosis; endothelial cells; role ... See more keywords
Photo by nci from unsplash

Macrophages Remember Cheeseburgers and Promote Inflammation via NLRP3.

Sign Up to like & get
recommendations! Published in 2018 at "Trends in molecular medicine"

DOI: 10.1016/j.molmed.2018.02.005

Abstract: In a recent study, Christ and colleagues identify a key role for NLRP3/IL-1beta in the induction of innate immune memory in monocytes by the Western diet, promoting atherosclerosis and inflammatory diseases. read more here.

Keywords: via nlrp3; macrophages remember; inflammation via; cheeseburgers promote ... See more keywords
Photo by osheen_ from unsplash

Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation

Sign Up to like & get
recommendations! Published in 2020 at "Nature Communications"

DOI: 10.1038/s41467-020-15497-1

Abstract: Oncogenic Ras mutations occur in various leukemias. It was unclear if, besides the direct transforming effect via constant RAS/MEK/ERK signaling, an inflammation-related effect of KRAS contributes to the disease. Here, we identify a functional link… read more here.

Keywords: myeloproliferation; via nlrp3; inflammasome activation; activation ... See more keywords
Photo by tcwillmott from unsplash

FERMT1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLRP3/NF-κB pathway.

Sign Up to like & get
recommendations! Published in 2023 at "Experimental animals"

DOI: 10.1538/expanim.22-0145

Abstract: Intracerebral hemorrhage (ICH) is an incurable neurological disease. Microglia activation and its related inflammation contribute to ICH-associated brain damage. FERM domain containing kindlin 1 (FERMT1) is an integrin-binding protein that participates in microglia-associated inflammation, but… read more here.

Keywords: inflammation; nlrp3 pathway; fermt1 knockdown; via nlrp3 ... See more keywords