Abstract 6557: Aescin, a triterpene saponin induces apoptosis & oxidative damage in human oral & laryngeal cancer cells via notch signaling
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DOI: 10.1158/1538-7445.am2020-6557
Abstract: The incidence of Head and Neck cancer in increasing worldwide. The major risk factor for these cancers includes viral infection, smoking, alcohol and tobacco consumption. Natural agents have often exhibited medicinal properties with usefulness in… read more here.
Keywords: via notch; damage; cancer; notch signaling ... See more keywords
Targeting Wnt Signaling via Notch in Intestinal Carcinogenesis
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DOI: 10.3390/cancers11040555
Abstract: Proliferation and differentiation of intestinal epithelial cells is assisted by highly specialized and well-regulated signaling cascades. The Wnt pathway, which is one of the fundamental pathways in the intestine, contributes to the organization of proliferative… read more here.
Keywords: targeting wnt; wnt signaling; via notch; signaling via ... See more keywords