One-Pot Protocol To Synthesize 2-Aminophenols from Anilines via Palladium-Catalyzed C–H Acetoxylation
Sign Up to like & getrecommendations! Published in 2019 at "Organometallics"
DOI: 10.1021/acs.organomet.9b00113
Abstract: This paper describes a facile one-pot protocol to synthesize 2-aminophenol derivatives via a palladium-catalyzed C–H acetoxylation strategy with 5-nitropyrimidine as a directing group (DG), which can be easily preinstalled and readily removed under mild condition… read more here.
Keywords: palladium catalyzed; one pot; protocol synthesize; via palladium ... See more keywords
Synthesis of meta-(Indol-3-yl)phenols from Indoles and Cyclohexenone via Palladium(II)-Catalyzed Oxidative Heck Reaction and Dehydrogenative Aromatization in a One-Step Sequence.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c02679
Abstract: Facile construction of a meta-(indol-3-yl)phenol framework with a wide substrate scope (a total of 25 compounds) via a palladium(II)-catalyzed oxidative Heck reaction and dehydrogenative aromatization in a one-step sequence is reported. This methodology affords a… read more here.
Keywords: meta indol; via palladium; palladium catalyzed; oxidative heck ... See more keywords
Ligand-Enabled C-H Olefination and Lactonization of Benzoic Acids and Phenylacetic Acids via Palladium Catalyst.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04000
Abstract: A novel ligand propan-2-one O-(p-tolylcarbamoyl) oxime (L7) has been developed to promote C(sp2)-H olefination of benzoic acids and phenylacetic acids via a palladium catalyst. With the subsequent lactonization of the olefinated products through 1,4-addition, highly… read more here.
Keywords: phenylacetic acids; acids phenylacetic; palladium catalyst; acids via ... See more keywords
Carbonylative Synthesis of Fused Quinoxalinones via Palladium-Catalyzed Cascade Cyclization of 2-Heteroaryl Iodobenzene and NaN3.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c01466
Abstract: A facile and straightforward approach for the synthesis of fused quinoxalinones via palladium-catalyzed cascade carbonylative cyclization of 2-heteroaryl iodobenzene and NaN3 has been achieved. The transformation might undergo cascade carbonylation, formation of acyl azide, a… read more here.
Keywords: quinoxalinones via; palladium catalyzed; synthesis fused; fused quinoxalinones ... See more keywords
Polycyclic Azetidines and Pyrrolidines via Palladium-Catalyzed Intramolecular Amination of Unactivated C(sp3)-H Bonds.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02339
Abstract: A novel strategy to construct complex polycyclic nitrogen-containing heterocycles from aliphatic amines via picolinamide-assisted palladium-catalyzed C-H bond activation reaction was reported. The reaction exhibits broad substrate scope for the synthesis of various azabicyclic scaffolds, including… read more here.
Keywords: via palladium; polycyclic azetidines; palladium catalyzed; pyrrolidines via ... See more keywords
General Strategy for Stereoselective Synthesis of β- N-Glycosyl Sulfonamides via Palladium-Catalyzed Glycosylation.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b01506
Abstract: A highly efficient and mild glycosylation reaction between 3,4- O-carbonate glycal and N-tosyl functionalized aliphatic and aromatic amines via palladium-catalyzed decarboxylative allylation is disclosed. A wide range of highly functionalized 2,3-unsaturated β- N-glycosides are furnished… read more here.
Keywords: glycosyl sulfonamides; via palladium; palladium catalyzed; glycosylation ... See more keywords
Tandem C-C/C-N Formation via Palladium-Catalyzed C-H Activation/Styrenation and Sequential Annulation of O-Methylketoxime with Styrenes.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b00702
Abstract: A novel route for tandem C-C/C-N formation via palladium-catalyzed C-H activation/styrenation and annulation of O-methylketoxime with styrenes to synthesize benzothienopyridines and benzofuropyridines has been developed. Furthermore, the intermolecular alkenylation of the ketoxime with acrylates produces… read more here.
Keywords: formation via; activation styrenation; via palladium; tandem formation ... See more keywords
Direct Assembly of Polysubstituted Propiolamidinates via Palladium-Catalyzed Multicomponent Reaction of Isocyanides.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b03201
Abstract: A straightforward approach for the assembly of different polysubstituted propiolamidnates via palladium-catalyzed multicomponent reaction of isocyanides, haloalkynes, and amines has been reported in which the C(sp)-C(sp2) and C(sp2)═N bonds were constructed in one pot. This… read more here.
Keywords: reaction isocyanides; multicomponent reaction; via palladium; palladium catalyzed ... See more keywords
Enantioselective Total Synthesis of (−)-Himalensine A via a Palladium and 4-Hydroxyproline Co-catalyzed Desymmetrization of Vinyl-bromide-tethered Cyclohexanones
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c13710
Abstract: Herein, we describe the convergent enantioselective total synthesis of himalensine A in 18 steps, enabled by a highly enantio- and diastereoselective construction of the morphan core via a palladium/hydroxy proline co-catalyzed desymmetrization of vinyl-bromide-tethered cyclohexanones.… read more here.
Keywords: himalensine; synthesis himalensine; via palladium; palladium ... See more keywords
Construction of a functionalized hierarchical pore metal-organic framework via a palladium-reduction induced strategy.
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale"
DOI: 10.1039/c9nr10092j
Abstract: Hierarchical porosity and functionalization are recognized as two crucial parameters in mediating the catalytic performance of heterogeneous catalysts, however, they are rarely achieved simultaneously in the development of metal-organic frameworks (MOFs). In this work, a… read more here.
Keywords: palladium reduction; metal organic; reduction induced; via palladium ... See more keywords
Synthesis of C3-alkylated benzofurans via palladium-catalyzed regiocontrolled hydro-furanization of unactivated alkenes
Sign Up to like & getrecommendations! Published in 2020 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo01247e
Abstract: A new chelation-controlled hydrofuranization of unactivated olefins with α-alkynyl arylols is reported for the first time, and used to produce a wide range of C3-alkylated benzofurans with generally good yields under mild conditions. A bidentate… read more here.
Keywords: alkylated benzofurans; synthesis alkylated; catalyzed regiocontrolled; via palladium ... See more keywords