Direct Access to Thiocyano-Thioesters from Cyclic Thioacetals via Photoredox Catalysis: An Introduction of Two Functional Groups in One Pot.
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DOI: 10.1021/acs.orglett.2c02601
Abstract: The cyanation of organic compounds is an important synthetic transformation and mainly relies on a toxic CN source. Undeniably, thiocyanate salt has emerged as a very mild and environmentally benign CN source, yet its synthetic… read more here.
Keywords: thiocyano thioesters; cyclic thioacetals; photoredox catalysis; via photoredox ... See more keywords
Iminoacylation of Alkenes via Photoredox N-Heterocyclic Carbene Catalysis.
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DOI: 10.1021/acs.orglett.3c00006
Abstract: The iminoacylation of alkenes via photoredox N-heterocyclic carbene catalysis is developed with the employment of alkene-tethered α-imino-oxy acids and acyl imidazoles. The corresponding substituted 3,4-dihydro-2H-pyrroles were afforded in moderate to good yields with good to… read more here.
Keywords: catalysis; via photoredox; iminoacylation alkenes; photoredox heterocyclic ... See more keywords
Azolation of Benzylic C-H Bonds via Photoredox-Catalyzed Carbocation Generation.
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DOI: 10.1021/jacs.2c12850
Abstract: A visible-light photoredox-catalyzed method is reported that enables the coupling between benzylic C-H substrates and N-H azoles. Classically, medicinally relevant N-benzyl azoles are produced via harsh substitution conditions between the azole and a benzyl electrophile… read more here.
Keywords: azolation benzylic; benzylic bonds; via photoredox; bonds via ... See more keywords
Site- and Stereoselective Synthesis of Alkenyl Chlorides by Dual Functionalization of Internal Alkynes via Photoredox/Nickel Catalysis.
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DOI: 10.1021/jacs.3c02748
Abstract: Herein, we report a redox-neutral and atom-economical protocol to synthesize valuable alkenyl chlorides from unactivated internal alkynes and abundant organochlorides via photoredox and nickel catalysis. This protocol enables the site- and stereoselective addition of organochlorides… read more here.
Keywords: internal alkynes; nickel catalysis; via photoredox; site stereoselective ... See more keywords
Enantioselective C-H bond functionalization of aromatic ketones with 1,6-enynes via photoredox/cobalt dual catalysis.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03595b
Abstract: An enantioselective ortho-C(sp2)-H functionalization of ketones with 1,6-enynes is demonstrated via photoredox/cobalt dual catalysis. The method exhibits high yields, functional group tolerance, and selectivity. Mechanistic studies suggested the operation of visible-light mediated low-valent cobalt complex… read more here.
Keywords: cobalt; via photoredox; ketones enynes; dual catalysis ... See more keywords