Articles with "via polar" as a keyword



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Oxindole synthesis via polar–radical crossover of ketene-derived amide enolates in a formal [3 + 2] cycloaddition

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Published in 2022 at "Chemical Science"

DOI: 10.1039/d1sc07134c

Abstract: Herein we introduce a simple, efficient and transition-metal free method for the preparation of valuable and sterically hindered 3,3-disubstituted oxindoles via polar–radical crossover of ketene derived amide enolates. Various easily accessible N-alkyl and N-arylanilines are… read more here.

Keywords: polar radical; via polar; amide enolates; ketene derived ... See more keywords