Articles with "via raney" as a keyword



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Practical synthesis of 16α-bromo-17α-hydroxysteroids via a Raney Ni-catalyzed bromide exchange reaction

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Published in 2019 at "Tetrahedron Letters"

DOI: 10.1016/j.tetlet.2019.05.049

Abstract: Abstract D-ring modified glucocorticoids are attractive synthetic targets owing to their broad application in medicinal chemistry. Herein, we reported a practical synthesis of 16α-bromo-17α-hydroxysteroids from easily available 16β-bromo isomers via a Raney Ni-catalyzed bromide exchange… read more here.

Keywords: via raney; reaction; bromo hydroxysteroids; synthesis bromo ... See more keywords