Pharmacokinetics and Pharmacodynamics of Antibody-Drug Conjugates Administered via Subcutaneous and Intratumoral Routes
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DOI: 10.3390/pharmaceutics15041132
Abstract: We hypothesize that different routes of administration may lead to altered pharmacokinetics/pharmacodynamics (PK/PD) behavior of antibody-drug conjugates (ADCs) and may help to improve their therapeutic index. To evaluate this hypothesis, here we performed PK/PD evaluation… read more here.
Keywords: administration; pharmacokinetics pharmacodynamics; via subcutaneous; drug conjugates ... See more keywords