Synthesis of Polycyclic Amides via Tandem RhIII‐Catalyzed C−H Activation and Annulation from Dioxazolones and Alkynes
Sign Up to like & getrecommendations! Published in 2017 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.201700140
Abstract: A highly efficient synthesis of polycyclic amides by Rh(III)-catalyzed cascade cyclization of 3-phenyl-1, 4, 2-dioxazol-5-one and diphenylacetylene has been developed. This novel one-pot strategy expanded the application scope of directing groups to dioxazolones. read more here.
Keywords: amides via; polycyclic amides; synthesis polycyclic; via tandem ... See more keywords
The synthesis of perfluoroalkylated indolizines via tandem cyclization/aromatization
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2021.109900
Abstract: Abstract The incorporation of a perfluoroalkyl group into heterocycles has received increasing attention. Herein we describe the synthesis of perfluoroalkylated indolizines via a tandem cyclization/aromatization process under mild conditions. In contrast to previous synthetic methods,… read more here.
Keywords: tandem cyclization; cyclization aromatization; indolizines via; via tandem ... See more keywords
Synthesis of bavachromanol from resorcinol via a tandem cationic cascade/EAS sequence
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2018.02.041
Abstract: Abstract The natural chalcone bavachromanol has been prepared through a tandem reaction sequence that joins cationic cyclization of an epoxide to an adjacent MOM-acetal with electrophilic aromatic substitution by a presumed methoxymethylene cation. Only a… read more here.
Keywords: via tandem; resorcinol via; bavachromanol resorcinol; sequence ... See more keywords
3,4-Annulated Indoles via Tandem Cyclopropane Ring-Opening/Conia-ene and Michael Addition/Conia-ene Reactions.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01810
Abstract: 4-Alkynyl indoles, when treated with a benzylidene malonate or a donor-acceptor cyclopropane in the presence of a zinc halide, furnished 3,4-hexannylated or 3,4-heptannulated products, respectively, in fair to excellent yields. The reaction proceeds via a… read more here.
Keywords: ene; via tandem; conia ene; cyclopropane ... See more keywords
Synthesis of Fluoranthene Derivatives via Tandem Suzuki–Miyaura and Intramolecular C–H Arylation Reactions under Both Homogeneous and Heterogeneous Catalytic Conditions
Sign Up to like & getrecommendations! Published in 2017 at "ACS Omega"
DOI: 10.1021/acsomega.7b01566
Abstract: A catalytic method for the synthesis of substituted fluoranthenes that operates via tandem Suzuki–Miyaura and intramolecular C–H arylation reactions is reported. The overall reaction sequence works effectively with homogeneous catalysis using Pd(dppf)Cl2 as well as… read more here.
Keywords: intramolecular arylation; via tandem; tandem suzuki; suzuki miyaura ... See more keywords
Synthesis of 2,3-disubstituted indoles via a tandem reaction
Sign Up to like & getrecommendations! Published in 2020 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo00765j
Abstract: A strategy for the synthesis of 2,3-disubstituted indoles from 2-allyl-2-(2-nitrophenyl)cyclohexane-1,3-dione has been developed. A wide array of 2,3-disubstituted indoles were accessed in modest to good yields via a tandem reduction/condensation/fragmentation/cyclization sequence. The utility of this… read more here.
Keywords: via tandem; tandem reaction; indoles via; synthesis disubstituted ... See more keywords