Synthesis of Trifluoromethyl‐Substituted Tetrazoles via KI/TBHP‐Mediated Oxidative Annulation of Trifluoroacetimidohydrazides and Nitromethane
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.70204
Abstract: A metal‐free strategy for the preparation of trifluoromethyl‐substituted tetrazoles via KI/TBHP‐mediated oxidative annulation of readily available trifluoroacetimidohydrazides (TFAIHs) and nitromethane has been disclosed. In this transformation, CH3NO2 is applied as both the inexpensive nitrogen synthon… read more here.
Keywords: mediated oxidative; tetrazoles via; substituted tetrazoles; via tbhp ... See more keywords