Synthesis of 1,4-Diketones via Titanium-Mediated Reductive Homocoupling of α-Haloketones
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DOI: 10.1055/s-0037-1610245
Abstract: 1,4-Diketones have been synthesized via a reductive homocoupling of α-haloketones. Addition of a Grignard reagent to titanium(IV) isopropoxide affords a low-valent titanium(III) intermediate that is believed to mediate a radical dimerization reaction. The reaction works… read more here.
Keywords: diketones via; via titanium; reductive homocoupling; synthesis diketones ... See more keywords