Online deployment of an O‐PLS model for dielectric spectroscopy‐based inline monitoring of viable cell concentrations in Chinese hamster ovary cell perfusion cultivations
Sign Up to like & getrecommendations! Published in 2023 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.202200053
Abstract: Viable cell concentration (VCC) is an essential parameter that is required to support the efficient cultivation of mammalian cells. Although commonly determined using at‐line or off‐line analytics, in‐line capacitance measurements represent a suitable alternative method… read more here.
Keywords: cell; viable cell; chinese hamster; spectroscopy ... See more keywords
Hypoxic pulmonary endothelial cells release epidermal growth factor leading to vascular smooth muscle cell arginase‐2 expression and proliferation
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DOI: 10.14814/phy2.15342
Abstract: The hallmark of pulmonary hypertension (PH) is vascular remodeling. We have previously shown that human pulmonary microvascular endothelial cells (hPMVEC) respond to hypoxia with epidermal growth factor (EGF) mediated activation of the receptor tyrosine kinase,… read more here.
Keywords: cell; viable cell; proliferation; hcm ... See more keywords
Screening Naturally Occurring Phenolic Antioxidants for Their Suitability as Additives to CHO Cell Culture Media Used to Produce Monoclonal Antibodies
Sign Up to like & getrecommendations! Published in 2019 at "Antioxidants"
DOI: 10.3390/antiox8060159
Abstract: This study identified several antioxidants that could be used in Chinese hamster ovary (CHO)cell culture media and benefit monoclonal antibody production. The flavan-3-ols, catechin, epicatechin, epigallocatechin gallate and gallocatechin gallate all had no detrimental effect… read more here.
Keywords: cell; cell culture; culture media; viable cell ... See more keywords